List of Publications

PEER-REVIEWED MANUSCRIPTS:

  1. Francis, W.R., Einhorn, T.A., and Fielding, J.W.:Osteoid Osteoma of the Thoracic Spine.CLIN. ORTHOP., 149:175 176, 1980.
  2. Einhorn, T.A., Lane, J.M., Burstein, A.H., Kopman, C.R, and Vigorita, V.J.:The Healing of Segmental Bone Defects Induced by Demineralized Bone Matrix. A Radiographic and Biomechanical Study.J. BONE JOINT SURG., 66A:274 279, 1984.
  3. Inserra, S., Einhorn, T.A., Vigorita, V.J., and Smith, A.G.: Intraosseous Xanthoma Associated with Hyperlipoproteinemia: A Case Report.CLIN. ORTHOP., 187:218-222, 1984.
  4. Einhorn, T.A.: Osteoporosis and Metabolic Bone Disease. ADV. ORTHOP SURG. 8:175 184, 1984.
  5. Lane, J.M., Healy, J., Schwartz, E.R., Vigorita, V.J., Schneider, R., Einhorn, T.A., Suda, M.D, and Robbins, W.:Treatment of Osteoporosis with Sodium Fluoride and Calcium: Effect on Vertebral Fracture Incidence and Bone Histomorphometry. ORTHOP. CLIN. NORTH AMERICA, 15:729 745, 1984.
  6. Bonnarens, F., and Einhorn, T.A.,:Production of a Standard Closed Fracture in Laboratory Animal Bone.J. ORTHOP. RES. 2:97 101, 1984.
  7. Einhorn, T.A., Gordon, S.L., Hummel, C.F., Siegel, S.A., Avitable, M.J., and Carty, R.P.:Matrix Vesicle Enzymes in Human Osteoarthritis.J. ORTHOP. RES., 3:160 169, 1985.
  8. Einhorn, T.A., Vigorita, V.J., and Teitcher, J.:Hyperphosphatasemia in an Adult:Clinical Roentgenographic and Histomorphometric Findings and Comparison to Classical Paget's Disease.CLIN. ORTHOP., 204:253 260, 1986.
  9. Einhorn, T.A., Vigorita, V.J., and Aaron, A.:Localization of Technetium 99m Methylene Diphosphonate in Bone using Microautoradiography. J. ORTHOP. RES., 4:180 187, 1986.
  10. Vigorita, V.J., Anand, V.S., and Einhorn, T.A.:Sampling Error in Diagnosing Hyperparathyroid Changes in Bone in Small Needle Biopsies. AM. J. SURG. PATH., 10 (2): 140 142, 1986.
  11. Einhorn, T.A., Bonnarens, F., and Burstein, A.H.:The Contributions of Dietary Protein and Mineral to the Healing of Experimental Fractures:A Biomechanical Study.J. BONE JOINT SURG., 68A:1389 1395, 1986.
  12. Phelps, K.R., Einhorn, T.A., Vigorita, V.J., Lieberman, R.L., and Uribarri, J.: Acidosis Induced Osteomalacia: Metabolic Studies and Skeletal Histomorphometry. BONE,7:171 179, 1986.
  13. Phelps, K.R., Einhorn, T.A., Vigorita, V.J., Lundin, A.P., and Friedman, E.A.: Fracture Healing with Deferoxamine Therapy in a Patient with Aluminum Associated Osteomalacia. TRANS. AM. SOC. ARTIF. INTERN. ORGANS, 32:198 200, 1986
  14. Einhorn, T.A.: Evaluation and Treatment Methods for Metabolic Bone Disease.CONTEMP. ORTHOP., 14:21 34, 1987.
  15. Vigorita, V.J., Einhorn, T.A., and Phelps, K.R.:The Microscopic Bone Pathology in Two Cases of Surgically Treated Secondary Hyperparathyroidism:A Report of a Distinct Skeletal Lesion. AM. J.SURG. PATH., 11:205-209, 1987.
  16. Einhorn, T.A., Boskey, A.L., Gundberg, C.M., Vigorita, V.J., Devlin,V.J., and Beyer, M.M.: The Mineral and Mechanical Properties of Bone in Chronic Experimental Diabetes. J. ORTHOP. RES., 6:317 323, 1988.
  17. Phelps, K.R., Vigorita, V.J., Bansal, M., and Einhorn, T.A.: Histochemical Localization of Iron but not Aluminum in a Case of Dialysis-Associated Osteomalacia. AM. J. MED., 84:775-780, 1988.
  18. Devlin, V.J., Einhorn, T.A., Gordon, S.L., Alvarez, E.V., and Butt, K.M.H.: Total Hip Replacement After Renal Transplantation. Long Term Follow up and Assessment of Metabolic Bone Status. J. ARTHROP., 3:205 214, 1988.
  19. Einhorn, T.A., Gundberg, C.M., Devlin, V.J., and Warman, J.: Fracture Healing and Osteocalcin Metabolism in Vitamin K Deficiency. CLIN. ORTHOP., 237:219-222, 1988.
  20. Jacobs, S.J., Gilbert, M.S., and Einhorn, T.A.: The Treatment Fractures in Uremic Bone Disease. Causes of Failure and Optimization of Healing. CONTEMP. ORTHOP., 18:23-35, 1989.
  21. Phelps, K.R., Einhorn, T.A., Vigorita, V.J., Jones, G., and Lundin, A.P.: Persistence of Dialysis Osteomalacia Despite Treatment with 24R,25 Dihydroxycholecalciferol. NEPHRON, 51:197-206, 1989.
  22. Verhaeghe, J., Suiker, A.M.H., Nyomba, B.L., Visser, W.J., Einhorn, T.A., Dequeker, J., and Bouillon, R.: Bone Mineral Homeostasis in Spontaneously Diabetic BB Rats, II. Impaired Bone Turnover and Decreased Osteocalcin Synthesis. ENDOCRINOLOGY, 124:573-582, 1989.
  23. Einhorn, T.A., Hirschman, A., Kaplan, C., Nashed, R., Devlin, V.J., and Warman, J.: Neutral Protein-Degrading Enzymes in Experimental Fracture Callus. J. ORTHOP. RES. 7:792-805, 1989.
  24. Horowitz, M.C., Coleman, D.L., Ryaby, J.T., and Einhorn, T.A.: Osteotropic Agents Induce the Differential Secretion of Granulocyte - Macrophage Colony-Stimulating Factor by the Osteoblast Cell Line MC3T3-E1. J. BONE MINER. RES., 4:911-921, 1989.
  25. Horowitz, M.C., Einhorn, T.A., Philbrick, W., and Jilka, R.L.: Functional and Molecular Changes in Colony Stimulating Factor Secretion by Osteoblasts. CONNECT. TISSUE RES., 20:159-168, 1989.
  26. Einhorn, T.A., and Grelsamer, R.: The Use of Bone Grafts for Support and Fixation in Revision Total Hip Arthroplasty. BULL. HOSP. JT. DIS. ORTHOP. INST., 49:10-20, 1989
  27. Schwartz, M.E., Harrington, E.B., Harrington, M., Miller, C.M., Einhorn, T.A., McGinnis, K., and Haimov M.: Above-knee Amputation in Patients with Prior Prosthetic Hip Surgery: A Caveat: J. VASC. SURG., 11:480-481, 1990.
  28. Labat, M.L., Bringuier, A-F., Chandra, A., Einhorn, T.A., and Chandra, P.: Retroviral Expression in Mononuclear Blood Cells Isolated from a Patient with Osteopetrosis (Albers-Schönberg Disease). J. BONE MINER. RES., 5:425-435, 1990.
  29. Verhaeghe, J., Van Herck, E.V., Visser, W.J., Suiker, M.H., Thomasset, M., Einhorn, T.A., Faierman, E., and Bouillon, R.: Bone and Mineral Metabolism in the Long-Term Diabetic BB Rat: Decreased Bone Turnover and Osteoporosis. DIABETES, 39:477-482, 1990.
  30. Einhorn, T.A.: Osteopenic Disease: Diagnosis and Treatment. CURR. ORTHOP., 4:190-197, 1990.
  31. Einhorn, T.A., Simon, G., Devlin, V.J., Warman, J., Sidhu, S.P.S., and Vigorita, V.J.: The Osteogenic Response to Distant Skeletal Injury. J. BONE JOINT SURG. 72A:1374-1378, 1990.
  32. Verhaeghe, J., Visser, W.J., Einhorn, T.A., and Bouillon, R: Osteoporosis and Diabetes: Lessons from the Diabetic BB Rat. HORM. RES., 34:245-248, 1990.
  33. Einhorn, T.A., and Majeska, R.J.: Neutral Proteases in Regenerating Bone. CLIN. ORTHOP., 262:286-297, 1991.
  34. Lisser, S.P., and Einhorn, T.A.:Fracture Surgery in Metabolic BoneDisease.CONTEMP. ORTHOP., 22:537-545, 1991.
  35. Einhorn, T.A.:Clinical Applications of Recombinant Gene Technology:Bone and Cartilage Repair.CELLS AND MATERIALS, 2:1-11, 1992.
  36. Majeska, R.J., Minkowitz, B., Bastian, W., and Einhorn, T.A.:Effects of Beta-Adrenergic Blockade in an Osteoblast-Like Cell Line.J. ORTHOP. RES., 10:379-384, 1992.
  37. Einhorn, T.A., Wakley, G.K., Linkhart, S., Rush, E.B., Maloney, S., Faierman, E., and Baylink, D.J.:Incorporation of Sodium Fluoride Into Cortical Bone Does Not Impair the Mechanical Properties of the Appendicular Skeleton in Rats.CALCIF. TISSUE INT., 51:127-131, 1992.
  38. Einhorn, T.A.:Bone Strength: The Bottom Line.CALCIF. TISSUE INT., 51:333-339, 1992.
  39. Pan, W.T., and Einhorn, T.A.:The Biochemistry of Fracture Healing.CURR. ORTHOP., 6:207-213, 1992.
  40. Perry, M.D., Mont, M.A., Einhorn, T.A., and Waller, J.D.:The Validity of Measurements Made on Standard Foot Orthoroentgenograms.FOOT ANKLE, 13:502-507, 1992.
  41. Majeska, R.J., Port, M., and Einhorn, T.A.:Attachment to Extracellular Matrix Molecules by Cells Differing in the Expression of Osteoblastic Traits.J. BONE MINER. RES., 8:277-289, 1993.
  42. Kaufman, J.J., and Einhorn, T.A.:Ultrasound Assessment of Bone.J. BONE MINER. RES., 8:517-525, 1993.
  43. Bab, I.A., and Einhorn, T.A.:Regulatory Role of Osteogenic Growth Polypeptides in Bone Formation and Hemopoiesis.CRIT. REV. EUKARYOT.GENE EXP., 3:31-46, 1993.
  44. Vanderschueren, D., Van Herck, E., Suiker, A.M.H., Visser, W.J., Schot, L.P.C., Chung, K., Lucas, T.S., Einhorn, T.A., and Bouillon, R.:Bone and Mineral Metabolism in the Androgen Resistant (Testicularized Feminized) Male Rat.J. BONE MINER. RES., 8:801-809, 1993.
  45. Lucas, T.S., and Einhorn, T.A.:Stress Fracture of the Femoral Neck During Rehabilitation After Heart Transplantation.ARCH. PHYS. MED. REHABIL., 74:1004-1006, 1993.
  46. Lucas, T.S., and Einhorn, T.A.:Osteoporosis:The Role of the Orthopaedist.J. AMER. ACAD. ORTHOP. SURG., 1:48-56, 1993.
  47. Vanderschueren, D., Van Herck, E., Schot, L., Rush, E., Einhorn, T., Guesens, P., and Bouillon R.:The Aged Male Rat as a Model for Human Osteoporosis:Evaluation by Non-Destructive Measurements and Biomechanical Testing.CALCIF. TISSUE INT., 53:342-347, 1993.
  48. Majeska, R.J., Ryaby, J.T., and Einhorn, T.A.:Direct Modulation of Osteoblastic Activity with Estrogen.J. BONE JOINT SURG., 76A:713-721, 1994.
  49. Sato, M., Garsky, V., Majeska, R.J., Einhorn, T.A., Murray, J., Tashjian, A.H., and Gould R.J.:Structure-Activity of the s-Eichistatin Inhibition of Bone Resorption.J. BONE MINER. RES., 9:1441-1449, 1994.
  50. Robinson, D., and Einhorn, T.A.:Giant Cell Tumor of Bone:A Unique Paradigm of Stromal-Hematopoietic Cellular Interactions.J. CELL BIOCHEM., 55:300-303, 1994.
  51. Bab, I.A., and Einhorn, T.A.:Polypeptide Factors Regulating Osteogenesis and Bone Marrow Repair.J. CELL. BIOCHEM., 55:358-365, 1994.
  52. Verhaeghe, J., Suiker, A.M.H., Einhorn, T.A., Geusens, P., Visser, W.J., Van Herck, E., Van Bree, R., Magitsky, S., and Bouillon, R.: Brittle Bones in Spontaneously Diabetic Rats Cannot Be Predicted by Bone Mineral Measurements. J. BONE MINER. RES., 9:1657-1667, 1994.
  53. Einhorn, T.A., and Kaplan, F.S.: Traumatic Fractures of Heterotopic Bone in Patients Who Have Fibrodysplasia Ossificans Progressiva - A Report of Two Cases. CLIN. ORTHOP., 308:173-177, 1994.
  54. Molinari, R.W., Yang, E.C., Strauss, E., and Einhorn, T.A.: Timing of Internal Fixation in Low-Velocity Gunshot Fractures. CONTEMP. ORTHOP. 29:335-339, 1994.
  55. Einhorn, T.A.: Current Concepts Review: Enhancement of Fracture Healing. J. BONE JOINT SURG., 77A:940-956, 1995.
  56. Silver, J.J., and Einhorn, T.A.: Osteoporosis and Aging: Current Update. CLIN. ORTHOP., 316:10-20, 1995.
  57. Einhorn, T.A., Majeska, R.J., Rush, E.B., Levine, P.M., and Horowitz, M.C.: The Expression of Cytokine Activity by Fracture Callus. J. BONE MINER. RES., 10:1272-1281, 1995.
  58. Pastores, G.M., and Einhorn, T.A.: Skeletal Complications of Gaucher Disease: Pathophysiology, Evaluation, and Treatment. SEMINARS HEMATOL., 32 (Suppl 1): 20-27, 1995
  59. Duursma, S.A., Aerts, J.M.F.G., Belmatoug, N., Cox, T.M., Einhorn, T.A., Esplin, J.A., Hollack, C.E.M., Incerti, C., Pastores, G. M., Rademakers, R., and Zaizov, R.:Management of Gaucher Disease - Current Status and Future Directions: A Roundtable Discussion. SEMINARS HEMATOL., 32 (Suppl 1):45-52, 1995.
  60. Mautelen, C.A., Vega, E.M., and Einhorn, T.A.: Are the Etiologies of Cervical and Trochanteric Hip Fractures Different? BONE, 18:133S-137S, 1996.
  61. Trippel, S.B., Coutts, R.D., Einhorn, T.A., Mundy, G.R., and Rosenfeld, R.G.: Growth Factors as Therapeutic Agents. J. BONE JOINT SURG., 78A:1272-1286, 1996.
  62. Verhaeghe, R., van Bree, R., Van Herck, E., Thomas, H., Skottner, A., Dequeker, J., Mosekilde, Li, Einhorn, T.A., and Bouillon, R.: Effects of Recombinant Human Growth Hormone and Insulin-like Growth Factor-1, With or Without 17b-Estradiol, on Bone and Mineral Homeostasis of Aged Ovariectomized Rats. J. BONE MINER. RES., 11:1723-1735, 1996.
  63. Melton, L.J., III, Thamer, M., Ray, N.F., Chan, J.K., Chesnut, C.H., III, Einhorn, T.A., Johnston, C.C., Raisz, L.G., Silverman, S.L., and Siris, E.S.: Fractures Attributable to Osteoporosis: Report from the National Osteoporosis Foundation. J. BONE MINER. RES., 12:16-23, 1997.
  64. Gottlieb, S. and Einhorn, T.A.: Current Concepts Review: Managed Care: Form, Function and Evolution. J. BONE JOINT SURG., 79A:125-136, 1997.
  65. Verhaeghe, J., Oloumi, G., Van Herck, E., Van Bree, R., Dequeker, J., Einhorn, T.A., and Bouillon, R. : Effects of Long-Term Diabetes and/or High Dose 17B-Estradiol on Bone Formation, Bone Mineral Density, and Strength in Ovariectomized Rats. BONE, 20:421-428, 1997.
  66. Lucas, T.S., Bab, I.A., Lian, J.B., Stein, G.S., Jazrawi, L., Majeska, R.J., Attar-Namdar, M., and Einhorn, T.A.: Stimulation of Systemic Bone Formation Induced by Experimental Blood Loss. CLIN ORTHOP., 340:267-275, 1997.
  67. Robinson, D., M.M., Nevo, Z., Kenan, S., and Einhorn, T.A.: The Radiographic State of Giant Cell Tumor Related to Stromal Cells' Proliferation: Tissue Cultures in 13 Cases. ACTA ORTHOP. SCAND., 68:294-297, 1997.
  68. Seo, E.-G., Einhorn, T. A., and Norman, A.W.: 24R, 25 - Dihydroxyvitamin D3: An Essential Metabolite for Both Normal Bone Integrity and Healing of Tibial Fractures in Chicks. ENDOCRINOLOGY, 138: 3864-3872, 1997.
  69. Yamazaki, M., Majeska, R.J., Yoshioka, H., Moriya, H., and Einhorn, T.A.: Spatial and Temporal Expression of Fibril Forming Minor Collagen Genes (Types V and XI) during Fracture Healing.J. ORTHOP.RES. 15: 757-764, 1997.
  70. Mont, M.A., Einhorn, T.A., Sponseller, P.D., and Hungerford, D.S.: The Trapdoor Procedure Using Autogenous Cortical and Cancellous Bone Grafts for Osteonecrosis of the Femoral Head. J. BONE JOINT SURG., 80B: 56-62, 1998.
  71. Jazrawi, L.M., Majeska, R.J.,Klein, M.L., Kagel, E., Strömberg, L., and Einhorn, T.A.: Bone and Cartilage Formation in an Experimental Model of Distraction Osteogenesis. J.ORTHOP. TRAUMA,12: 111-116, 1998.
  72. Brunelli, M.P., and Einhorn, T.A.: Medical Management of Osteoporosis: Fracture Prevention. CLIN. ORTHOP., 15-21, 1998.
  73. Lee, F. Y-I., Choi, Y.W., Behrens, F.F., DeFouw, D.O., and Einhorn, T.A.: Programmed Removal of Chondrocytes During Endochondral Fracture Healing. J. ORTHOP. RES., 16: 144-150, 1998.
  74. Gottlieb, S., and Einhorn, T.A.,: Beyond HMOs: Understanding the Next Wave of Change in Health-Care Organization. J. AMER. ACAD. ORTHOP. SURG., 6:75-83, 1998.
  75. Sanzone, A.G. and Einhorn, T.A.: The Use of Bone Morphogenetic Proteins to Heal Fractures, Articular Cartilage Defects, and Ligament and Tendon Injuries. SPORTS MED. AND ARTHROSC. REV., 6:118-123, 1998.
  76. Kato, A., Seo, E.-G., Einhorn, T.A, Bishop, J.E. and Norman, A.W.: Studies on 24R, 25-Dihydroxyvitamins D3: Evidence for a Non-Nuclear Membrane Receptor in Chick Tibial Fracture-Healing Callus. BONE, 23: 141-146, 1998.
  77. Einhorn, T.A.: The Cell and Molecular Biology of Fracture Healing. CLIN. ORTHOP., 355S: S7-S21, 1998.
  78. Mont, M.A., Jones, L.C., Einhorn, T.A., Hungerford, D.S., and Reddi, A.H.: Osteonecrosis of the Femoral Head: Potential Treatment with Growth and Differentiation Factors. CLIN. ORTHOP., 355S:S314-S335, 1998.
  79. Mirsky, E.C., and Einhorn, T.A.: Bone Densitometry in Orthopaedic Practice. J. BONE JOINT SURG., 80A:1687-1698, 1998.
  80. Yamazaki, M., Majeska, R.J., Nakajimi, F., Ogasawara, A. Moriya, H., and Einhorn, T.A.: Spatial and Temporal Distribution of CD44 and Osteopontin in Fracture Callus. J. BONE JOINT SURG., 81B: 516-521, 1999.
  81. Holzer, G., Majeska, R.J., Lundy, M.W., Hartke, J.R. and Einhorn, T.A.: Parathyroid Hormone Enhances Experimental Fracture Healing. A Preliminary Report. CLIN.ORTHOP., 366:258-263, 1999.
  82. Einhorn, T.A.: Clinically Applied Models of Bone Regeneration in Tissue Engineering Research. CLIN. ORTHOP. S59-S67, 1999.
  83. Barnes, G. L., Kostenuik, L. J., Gerstenfeld, L. C., and Einhorn, T. A. : Growth Factor Regulation of Fracture Healing. J. BONE MINER. RES., 14:1805-1815, 1999.
  84. Kon, T., Cho, T.-J., Aizawa, T., Yamazaki, M., Nooh, N., Graves, D., Gerstenfeld, L. C. and Einhorn, T. A. : Expression of Osteoprotegerin, Receptor Activator of NF-?B Ligand (Osteoprotegerin Ligand) and Related Pro-Inflammatory Cytokines During Fracture Healing. J. BONE MINER. RES., 16:1004-1014, 2001.
  85. Weisstein, J. S., Majeska, R. J., Klein, M. J. and Einhorn, T. A. : Detection of c-fos Expression in Benign and Malignant Musculoskeletal Lesions. J. ORTHOP. RES., 19:339-345, 2001.
  86. Einhorn, T. A. and Lee, C. A.: Bone Regeneration: New Findings and Potential Clinical Applications. J. AM. ACAD. ORTHOP. SURG., 9:157-165, 2001.
  87. Gerstenfeld, L. C., Cho, T-J, Kon, T., Aizawa, T., Cruceta, J., Graves, B. D., and Einhorn, T. A.: Impaired Intramembranous Bone Formation During Bone Repair in the Absence of TNF-? Signaling. CELLS TISSUES ORGANS ,169:285-94, 2001.
  88. Aizawa, T., Kon, T., Einhorn, T. A. and Gerstenfeld, L. C.: Induction of Apoptosis in Chondrocytes by Tumor Necrosis Factor-?. J. ORTHOP. RES., 19:785-796, 2001.
  89. Nakajima, F., Ogasawara, A., Goto, K-I., Moriya, H., Ninomiya, Y., Einhorn, T. A. and Yamazaki, M.: Spatial and Temporal Gene Expression in Chondrogenesis during Fracture Healing and the Effects of Basic Fibroblast Growth Factor. J. ORTHOP. RES., 19:935-944, 2001.
  90. Nakajima, A., Nakajima, S., Shimizu, S., Ogasawara, A., Wanaka, A., Moriya, H., Einhorn, T. A. and Yamazaki, M.: Spatial and Temporal Gene Expression for Fibroblast Growth Factor Type I Expression during Fracture Healing in the Rat. BONE, 29:458-466, 2001.
  91. Gerstenfeld, L. C., Cruceta, J., Shea, C. M., Sampath, K., Barnes, G. and Einhorn, T. A.: Chondrocytes Provide Morphogenic Signals that Selectively Induce Osteogenic Differentiation in Mesenchymal Stem Cells. J. BONE MINER. RES., 17:221-230, 2002.
  92. Cho, T-J., Gerstenfeld, L. C. and Einhorn, T. A.: Differential Temporal Expression of Members of the TGF-? Superfamily during Murine Fracture Healing. J. BONE MINER. RES., 17:513-520, 2002.
  93. Holzer, G., Einhorn, T. A. and Majeska, R. J.: Estrogen Regulation of Growth and Alkaline Phosphatase Expression by Cultured Human Bone Marrow Stromal Cells. J. ORTHOP. RES., 20:281-294, 2002 .
  94. Kinner, B., Gerstenfeld, L. C., Einhorn, T. A. and Spector, M.: Expression of Smooth Muscle Actin in Connective Tissue Cells Participating in Fracture Healing in a Murine Model. BONE, 5:738-745, 2002.
  95. Cullinane, D. M., Fredrick, A., Eisenberg, S. R., Pacicca, D., Elman, M. V., Lee, C., Salisbury, K., Gerstenfeld, L. C. and Einhorn, T. A.: Induction of a Neoarthrosis by Precisely Controlled Motion in an Experimental Mid-Femoral Defect. J. ORTHOP. RES., 20:579-586, 2002.
  96. Lieberman, J. R., Daluski, A. and Einhorn, T. A.: Current Concepts Review: The Role of Growth Factors in the Repair of Bone: Biology and Potential Clinical Applications. J. BONE JOINT SURG.., 84A:1032-1044, 2002.
  97. Nakajima, A., Shimoji, N., Shiomi, K., Shimizu, S., Moriya, H., Einhorn, T. A. and Yamazaki, M.: Mechanisms for the Enhancement of Fracture Healing in Rats Treated with Intermittent Low Dose Human Parathyroid Hormone(1-34). J. BONE MINER. RES., 17:2038-2047, 2002.
  98. Bhattacharyya, T., Gale, D., Dewire, P., Trotterman, S., Gale, M. E., Einhorn, T. A., McLaughlin, S. and Felson, D.: The Clinical Importance of Meniscal Tears Found by Magnetic Resonance Imaging of the Osteoarthritic Knee. J. BONE JOINT SURG., 85A:4-9, 2003.
  99. Kinner, B., Pacicca, D. M., Gerstenfeld, L. C., Lee C., Einhorn, T. A. and Spector, M.: Expression of Smooth Muscle Actin in Cells Involved in Distraction Osteogenesis in a Rat Model. J. ORTHOP. RES. 21:20-27, 2003.
  100. Einhorn, T. A.: Cox-2: Where are we in 2003? - The Role of Cyclooxygenase-2 in Bone Repair. ARTHRITIS RES. THER., 5:5-7, 2003.
  101. Gerstenfeld, L. C., Cullinane, D. M., Barnes, G. L., Graves, D. T. and Einhorn, T. A : Fracture Healing as a Post-natal Developmental Process: Molecular, Spatial, and Temporal Aspects of its Regulation. J. CELL BIOCHEM., 88:873-884, 2003.
  102. Gerstenfeld, L.C., Barnes, G. L., Shea, M. and Einhorn, T. A.: Osteogenic Differentiation Is Selectively Promoted by Morphogenetic Signals From Chondrocytes and Synergized by a Nutrient Rich Growth Environment. CONN. TISSUE RES. 44(Suppl.1):85-91, 2003.
  103. Gerstenfeld, L. C., Thiede, M., Seibert, K., Mielke, C., Phippard, D., Svagr, B., Cullinane, D. and Einhorn, T. A. : Differential Inhibition of Fracture Healing by Non-Selective and Cyclooxygenase-2 Selective Non-Steroidal Anti-Inflammatory Drugs. J. ORTHOP. RES. 21:670-675, 2003.
  104. Cullinane, D. M., Salisbury, K. T., Alkhiary, Y., Eisenberg, S., Gerstenfeld, L., and Einhorn, T. A.: Effects of the Local Mechanical Environment on Vertebrate Tissue Differentiation during Repair: Does Repair Recapitulate Development? J. EXP. BIOL., 206:2459-2471, 2003.
  105. Bhattacharyya, T., Tornetta, P., Healy, W. L., and Einhorn, T. A.: The Validity of Supporting Data for Claims Made in Orthopaedic Print Advertisements. J. BONE JOINT SURG. 85A:1224-1228, 2003.
  106. Einhorn, T. A., Majeska, R. J., Mohaideen, A., Kagel, E. M., Bouxsein, M. L., Turek, T. J. and Wozney, J. M.: A Single Percutaneous Injection of Recombinant Human Bone Morphogenetic Protein-2 Accelerates Fracture Repair. J. BONE JOINT SURG. 85A:1425-1435, 2003.
  107. Bhandari, M., Einhorn, T. A., Swiontkowski, M. F, and Heckman, J. D.: Who Did What? (Mis) Perceptions About Authors’ Contributions to Scientific Articles Based Upon Authorship Order. J. BONE JOINT SURG. 85A:1605-1609, 2003.
  108. Einhorn, T. A.: Clinical Applications of Recombinant Human BMPs: Early Experience and Future Development. J. BONE JOINT SURG. 85A(Suppl. 3):82-88, 2003.
  109. Gerstenfeld, L.C., Cho, T-J., Kon, T., Aizawa, T., Tsay, A., Barnes, G. L., Graves, D. T., and Einhorn, T. A.: Impaired Fracture Healing in the Absence of Tumor Necrosis Factor-? Signaling: The Role of TNF-a in Endochondral Cartilage Resorption. J. BONE MINER. RES., 18:1584-1592, 2003.
  110. Cho, T. J., Lehmann, W., Edgar, C., Sadeghi, C., Hou, A., Einhorn, T. A. and Gerstenfeld, L. C.: Tumor Necrosis Factor Alpha Activation of the Apoptotic Cascade in Murine Articular Chondrocytes Is Associated with the Induction of Metalloproteinases and Specific Pro-resorptive Factors. ARTHRITIS RHEUM., 48:2845-2854, 2003.
  111. Gerstenfeld, L. C. and Einhorn, T. A.: Developmental Aspects of Fracture Healing and and the Use of Pharmacological Agents to Alter Healing. J. MUSCULOSKEL. NEURON INTERACT., 3:297-303, 2003.
  112. Bono, C. M. and Einhorn, T. A.: Overview of Osteoporosis: Pathophysiology and Determinants of Bone Strength. EUR. SPINE J., 12:Suppl 2:S90-96, 2003
  113. Shea, C. M., Edgar, C. M., Einhorn, T. A., and Gerstenfeld, L. C.: BMP Treatment of C3H10T1/2 Mesenchymal Stem Cells Induces Both Chondrogenesis and Osteogenesis. J. CELL BIOCHEM, 15:1112-1127, 2003.
  114. Pacicca, D. M., Patel, N., Lee, C., Salisbury, K., Lehman, W., Carvalho, R., Gerstenfeld, L.C., and Einhorn, T. A.: Expression of Angiogenic Factors during Distraction Osteogenesis. BONE, 33:889-898, 2003.
  115. Schmidmaier, G., Wildemann, B., Melis, B., Krummrey, G., Einhorn, T. A., Haas, N. P. And Raschke, M.: Development and Characterization of a Standard Closed Tibial Fracture Model in the Rat. EUR. J. TRAUMA, 30:35-42, 2004.
  116. Gerstenfeld, L. C. and Einhorn, T. A.: COX Inhibitors and Their Effects on Bone Healing. EXPERT OPIN. DRUG SAF., 2:131-136, 2004.
  117. Nakazawa, T., Nakajima, A., Seki, N., Okawa, A., Kato, M., Moriya, H., Amizuka, N., Einhorn, T.A. and Yamazaki, M.: Gene Expression of Periostin in the Early Stage of Fracture Healing Detected by cDNA Microarray Analysis. J. ORTHOP. RES., 22:520-525, 2004.
  118. Carvalho, R. S., Einhorn, T. A., Lehman, W., Edgar, C., Alyamani, A., Apazidis, A., Pacicca, D., Clemens, T. L., and Gerstenfeld, L. C.: The Role of Angiogenesis in a Murine Model of Distraction Osteogenesis. BONE 34:849-861, 2004.
  119. Barnes, G. L., Hebert, K., Kamal, M., Javed, A., Einhorn, T. A., Lian, J.B., Stein, G. S., and Gerstenfeld, L. C.: Fidelity of Runx2 Activity in Breast Cancer Cells is Required for the Generation of Metastases Associated Osteolytic Disease. CANCER RES., 64:4506-4513, 2004.
  120. Bhandari, M., Swiontkowski, M., Einhorn, T. A., Tornetta III, P., Schemitsch, E., and Wright, J., G.: Inter-observer Agreement in the Application of the Levels of Evidence to Scientific Papers in The Journal of Bone and Joint Surgery. J. BONE JOINT SURG., 86A:1717-1720, 2004.
  121. Lochner, H. V. and Einhorn, T. A. : Advances in Therapeutic Diagnostics: Hormone Replacement Therapy. J. AMER. ACAD. ORTHOP. SURG., 12:291-294, 2004.
  122. Kim, H. J. W., Bian, H., Randall, T., Garces, A., Gerstenfeld, L. C., and Einhorn, T. A.: Increased VEGF Expression in the Epiphyseal Cartilage Following Ischemic Necrosis of the Capital Femoral Epiphysis. J. BONE MINER. RES., 19:2041-2048, 2004.
  123. Lehmann, W., Schinke, T., Catala-Lehnen, P., Gebauer, M., Pogoda, P., Gerstenfeld, L.C., Rueger, J.M., Einhorn, T. A., and Amling, M.: Absence of Mouse Pleiotrophin Does Not Affect Bone Formation In Vivo. BONE, 35:1247-1255, 2004.
  124. Mont, M. A., Ragland, P. S., Biggins, B., Friedlaender, G., Patel, T., Cook, S., Etienne, G., Shimmin, A., Kildey, R., Rueger, D.C., and Einhorn, T. A.: Use of Bone Morphogenetic Proteins for Musculoskeletal Applications: An Overview. J. BONE JOINT SURG., 86A:S2:41-55, 2004.
  125. Bhandari, M., Bajammal, S., Guyatt, G. H., Griffith, L., Busse, J., W., Schunermann, H., and Einhorn, T., A.:The Effect of Bisphosphonates on Periprosthetic Bone Mineral Density After Total Joint Arthroplasty. A Meta-Analysis. J. BONE JOINT SURG., 87A:293-301, 2005.
  126. Lehmann, W., Edgar, C. M., Wang, K., Cho, T-J., Barnes, G. L., Kakar, S., Graves, D. T., Rueger, J. M., Gerstenfeld, L. C., and Einhorn, T. A.: Tumor Necrosis Factor Alpha (TNF-?) Coordinately Regulates the Expression of Specific Matrix Metalloproteinases (MMPs) and Angiogenic Factors During Fracture Healing. BONE, 36:300-310, 2005.
  127. Alkhiary, Y. M., Gerstenfeld, L. C., Krall, E., Westmore, M., Sato, M., Mitlak, B. H., and Einhorn, T. A.: Enhancement of Experimental Fracture Healing by Systemic Administration of Recombinant Human Parathyroid Hormone (PTH 1-34). J. BONE JOINT SURG., 87:731-741, 2005.
  128. Purvis, J. M., Alexander, A. H., Einhorn, T. A., and Griffin, L. Y.: Evaluating the Flood or Orthopaedic Media and Marketing Information. J BONE JOINT SURG., 87A:1392-1398, 2005.
  129. Morris, C. D., and Einhorn, T. A. :Current Concepts Review: Bisphosphonates in Orthopaedic Surgery. J BONE JOINT SURG., 87A:1609-1618, 2005.
  130. Gerstenfeld, L. C., Wronski, T. J., Hollinger, J.O., and Einhorn, T. A.: Application of Histomorphometric Methods to the Study of Bone Repair. J. BONE MINER. RES., 20:1715-1722, 2005.
  131. Nakazawa, T., Nakajima, A., Shiomi, K., Moriya, H., Einhorn, T.A. and Yamazaki, M.: Effects of Low-dose, Intermittent Treatment with Recombinant Human Parathyroid Hormone (1-34) on Chondrogenesis in a Model of Experimental Fracture Healing. BONE, 37:711-719, 2005.
  132. Kain, M. S, and Einhorn, T. A.: Recombinant Human Bone Morphogenetic Proteins in the Treatment of Fractures. FOOT ANKLE CLIN., 10:639-650, 2005.
  133. Boden, S. D., Einhorn, T. A., Morgan, T. S., Tosi, L. L., and Weinstein, J. N.: An AOA Critical Issue. The Future of the Orthopaedic Surgeon - Proceduralist of Keeper of the Musculoskeletal System? J. BONE JOINT SURG., 87A:2812-2821, 2005.
  134. Einhorn, T. A. : The Science of Fracture Healing. J. ORTHOP. TRAUMA, 19(Suppl)S3-S6, 2005.
  135. Betz, O. B., Betz, V. M., Nazarian, A., Pilapil, C., G., Vrahas, M., S., Bouxsein, M., L., Gerstenfeld, L., C., Einhorn, T. A., and Evans, C., H.: Direct Percutaneous Gene Delivery to Enhance Healing of Segmental Bone Defects. J. BONE JOINT SURG., 88A:355-365, 2006.
  136. Boes, M., Kain, M., Kakar,S., Nichols, F., Cullinane, D., Gerstenfeld, L. C., Einhorn, T. A., and Tornetta, P. T. 3rd: The Osteogenic Effects of Traumatic Brain Injury in Experimental Fracture Healing. J. BONE JOINT SURG., 88A:738-743, 2006.
  137. Wang, K., Vishwanath, P., Eichler, G. S., Al-Sebai, M. O., Edgar, C. M., Einhorn, T. A., Smith, T. F., Gerstenfeld, L. C.: Analysis of Fracture Healing by Large Scale Transcriptional Profile Identified Temporal Relationships between Metalloproteinase and ADAMTs mRNA Expression. MATRIX BIOL., 25:271-281, 2006.
  138. Einhorn, T. A.: Funding the Mandate for the Orthopaedic Clinician Scientist. CLIN. ORTHOP. RELAT. RES., 449: 76 - 80, 2006.
  139. Gerstenfeld, L. C., Alkhiary, Y. M., Krall, E A., Nicholls, F. H., Stapelton, S. N., Fitch, J. L., Bauer, M., Kayal, R., Graves, D. T., Jepsen, K. J., and Einhorn,T. A : Three-dimensional Reconstruction of Fracture Callus Morphogenesis. J. HISTOCHEM. CYTOCHEM., 54:1215-1228, 2006.
  140. Gruber, R., Koch, H., Doll, B. A., Tegtmeier, F., Einhorn, T. A., and Hollinger, J. O.: Fracture Healing in the Elderly Patient. EXP. GERONTO., 11:1080-1093, 2006.
  141. Tsuji, K., Bandyopadhyay, A., Harfe, B. D., Cox, K., Kakar, S., Gerstenfeld, L., Einhorn, T., Tabin, C. J., and Rosen, V.: BMP2 Activity, Although Dispensable for Bone Formation, is Required for the Initiation of Fracture Healing. NAT, GENET., 12:1424-1429, 2006.
  142. Gerstenfeld, L. C., Al-Ghawas, M., Alkhiary, Y. M., Cullinane, D. M., Krall, E. A., Fitch, J. L., Webb, E. G., Thiede, M. A., and Einhorn, T. A.: Selective and Non-selective Cyclooxygenase-2 Inhibitors and Experimental Fracture-Healing. Reversibility of Effects after Short-term Treatment. J. BONE JOINT SURG., 89:114-125, 2007.
  143. De Long, W. G., Jr., Einhorn, T. A., Koval, K., McKee, M., Smith, W., Sanders, R., and Watson, T.: Bone Grafts and Bone Graft Substitutes in Orthopaedic Trauma Surgery. A Critical Analysis J BONE JOINT SURG., 89A:649-658, 2007.
  144. Marsell, R., Jonsson, K. B., Cho, T-J., Einhorn, T. A., Ohlsson, C., Schipani, E.: Mice Expressing a Consitutively Active PTH/PTHrP Receptor in Osteoblasts Show Reduced Callus Size but Normal Callus Morphology During Fracture Healing. ACTA ORTHOP. SCAND., 78:39-45, 2007.
  145. Kayal, R. A., Tsatsas, D., Bauer, M. A, Allen, B., Al-Sebaei, M.O., Kakar S, Leone, C.W., Morgan, E.F., Gerstenfeld, L, Einhorn, T.A., Graves, D.T.: Diminished Bone Formation during Diabetic Fracture Healing is Related to. the Premature Resorption of Cartilage Associated with Increased Osteoclast Activity. J BONE MINER RES., 22:560-568, 2007.
  146. Axelrad, T. W., Kakar, S., and Einhorn, T. A.: New Technologies for the Enhancement of Skeletal Repair. INJURY 38(Suppl) 1: S49-62, 2007.
  147. Saleh, K. J., Quick, J. C., Conaway, M., Sime, W. E., Martin, W., Hurwitz, S., and Einhorn, T. A.: The Prevalence and Severity of Burnout among Academic Orthopaedic Departmental Leaders. J BONE JOINT SURG. 89A:896-903, 2007.
  148. Edgar, C. M., Chakravarthy, V., Barnes, G. L., Kakar, S., Gerstenfeld, L. C., and Einhorn, T. A.: Autogenous Regulation of a Network of Bone Morphogenetic Proteins (BMPs) Mediates the Osteogenic Differentiation in Murine Marrow Stromal Cells. BONE, 40:1389-1398, 2007.
  149. Cho, T.J., Kim, J.A., Chung CY, Yoo, W.J., Gerstenfeld, L.C., Einhorn, T.A., and Choi, I.H.: Expression and Role of Interleukin-6 in Distraction Osteogenesis. CALCIF. TISSUE INT., 80:192-200, 2007.
  150. Bhandari, M., Busse, J., Devereaux, P. J., Momtori, V., M., Swiontkowski, M., Tornetta, P., Einhorn, T. A., Khera, T. A., and Schemitsch, E. H.: Factors Associated with Citation Rates in the Orthopaedic Literature. CAN. J. SURG., 50:119-123, 2007.
  151. Restrepo, C., Parvizi, J., Dietrich, T., and Einhorn, T. A.: Safety of Simultaneous Bilateral Total Knee Arthroplasty. A Meta-analysis. J. BONE JOINT SURG., 89A:1220-1226, 2007.
  152. Betz, O. B., Betz, V.M., Nazarian, A., Egermann,M., Gerstenfeld, L.C., Einhorn,T.A., Vrahas, M.S., Bouxsein, M.L., Evans, C.H.: Delayed Administration of Adenoviral BMP-2 vector Improves the Formation of Bone in Osseous Defects. GENE THER., 14:1039-1044, 2007.
  153. Tsiridis, E., Morgan, E. F., Bancroft, J. M., Song, M., Kain, M., Gerstenfeld, L., Einhorn, T. A., Bouxsein, M. L., Tornetta, P. 3rd: Effects of OP-1 and PTH in a New Experimental Model for the Study of Metaphyseal Bone Healing. J ORTHOP. RES., 25:1193-1203, 2007.
  154. Bishop, G. B, and Einhorn, T. A.: Current and Future Clinical Applications of Bone Morphogenetic Proteins in Orthopaedic Trauma Surgery. INT. ORTHOP., 31:721-727, 2007.
  155. Kakar, S., Einhorn, T. A., Vora, S., Hon, G., Wigner, N. A., Toben, D., Jacobsen, K., A., Al-Sebaei, M., O., Song, M., Trackman, P., C., Morgan, E., F., Gerstenfeld, L., C., and Barnes, G., L.: Enhanced Chondrogenesis and Wnt-signaling in Parathyroid Hormone Treated Fractures. J BONE MINER. RES., 22:1903 - 1912, 2007.
  156. Giannoudis, P. V., Kanakis, N., K., and Einhorn, T. A.: Interaction of Bone Morphogenetic Proteins with Cells of the Osteoclast Lineage: Review of the Existing Evidence. OSTEOPOROSIS INT., 18:1565-1581, 2007.
  157. Betz, V. M., Betz, O. B., Glatt, V., Gerstenfeld, L., C., Einhorn, T. A., Bouxsein, M., L., Vrahas, M., S., and Evans, C., H.:Healing of Segmental Bone Defects by Direct Percutaneous Gene Delivery: Effect of Vector Dose. HUM. GENE THER., 18:907-915, 2007.
  158. Giannoudis, P. V., Einhorn, T. A., and Marsh, D.: Fracture Healing: The Diamond Concept. INJURY 38 Suppl 4:S3-6, 2007.
  159. Hollinger, J., O., Onikepe, A., O., Mackrell, J., Einhorn, T., A., Bradica, G., Lynch, S., and Hart, C., E.: Accelerated Fracture Healing in the Geriatric, Osteoporotic Rat with Recombinant Human Platelet-derived Growth Factor-BB and an Injectable Beta-Tricalcium Phosphate/Collagen Matrix. J ORTHOP. RES., 26: 83 - 90, 2008.
  160. Wan, C., Gilbert, S. R., Wang, Y., Cao, X., Ramaswamy, G., Jacobsen, K. A., Alaql, Z., S., Eberhardt, A.W., Gerstenfeld, L. C., Einhorn, T., A., Deng, L., Clemens, T., L.: Activation of the Hypoxia-inducible factor-1 {alpha} Pathway Accelerates Bone Regeneration. PROC. NATL. ACAD. SCI. USA 105:686 - 689, 2008.
  161. Ai-Aql, Z. S., Alagl, A. S., Graves, D. T., Gerstenfeld. L. C., and Einhorn, T. A.:Molecular Mechanisms Controlling Bone Formation during Fracture Healing and Distraction Osteogenesis. J. DENT. RES., 87:107-118, 2008.
  162. Einhorn, T. A., Laurencin, C. T., and Lyons, K.: An AAOS-NIH Symposium. Fracture Repair: Challenges, Opportunities, and Directions for Future Research. J. BONE JOINT SURG., 90A:438-442, 2008.
  163. Barnes, G. L, Kakar, S., Vora, S., Morgan, E. F., Gerstenfeld, L. C, and Einhorn, T. A.: Stimulation of Fracture-Healing with Systemic Intermittent Parathyroid Hormone Treatment., J. BONE JOINT SURG., 90A(Suppl 1):120-127, 2008.
  164. Sung, J. K., Levin, R., Siegel, J., Einhorn, T. A., Creevy, W. R., and Tornetta, P.: Reuse of External Fixation Components: A Randomized Trial. J. ORTHOP. TRAUMA, 22:126-131, 2008.
  165. Jacobsen, K. A., Al-Aql, Z. S., Wan, C., Fitch, J. L., Stapleton, S., N., Mason, Z., D., Cole, R., M., Gilbert, S., R., Clemens, T., L., Morgan, E., F., Einhorn, T., A., and Gerstenfeld, L., C.: Bone formation during distraction osteogenesis is dependent on both VEGFR1 and VEGFR2 signaling. J BONE MINER. RES., 23:596-609, 2008.
  166. Jepsen, K., Price, C., Silkman, L., Nicholls, F., Nasser, P., Hu, B., Hadi, N., Alapatt, M., Stapleton, S., Kakar, S., Einhorn, T., and Gerstenfeld, L.: Genetic Variation in the Patterns of Skeletal Progenitor Cell Differentiation and Progression During Endochondral Bone Formation Affects the Rate of Fracture Healing. J. BONE MINER. RES., 23:1204-1216 2008.
  167. Bajammal, S. S., Zlowodzki, M., Lelwica, A., Tornetta, P., Einhorn, T. A., Buckley, R., Leighton, R., Russell, T. A., Larsson, S., and Bhandari, M.: The Use of Calcium Phosphate Bone Cement in Fracture Treatment. A Meta-Analysis of Randomized Trials. J. BONE JOINT SURG., 90(A):1186-1196, 2008.
  168. Giannoudis, P. V., Einhorn, T. A., and Schmidmaier, G., and Marsh, D.: The Diamond Concept - Open Questions. INJURY 39 Suppl 2:S3-6, 2008.
  169. Mollon, B., da Silva, V., Busse, J. W., Einhorn, T. A., and Bhandari, M: Electrical Stimulation for Long-Bone Fracture-Healing: A Meta-Analysis of Randomized Controlled Trials. J. BONE JOINT SURG., 90A:2322-2330, 2008.
  170. Axelrad, T., W., Steen, B., Lowenberg, D., W., Creevy, W., R., and Einhorn, T., A.: Heterotopic Ossification after the Use of Commercially Available Recombinant Human Bone Morphogenetic Proteins in Four Patients. J. BONE JOINT SURG., 90B:1617 - 1622, 2008.
  171. Morgan, E. F., Mason, Z. D., Bishop, G., Davis, A. D., Wigner, N. A., Gerstenfeld, L. C., and Einhorn, T. A. : Combined Effects of Recombinant Human BMP-7 (rhBMP-7) and Parathyroid Hormone (1-34) in Metaphyseal Bone Healing. BONE, 43:1031- 1038, 2008.
  172. Kayal, R. A., Alblowi, J., McKenzie, E., Krothapalli, N., Silkman, L., Gerstenfeld, L, Einhorn, T. A., and Graves, D.T: Diabetes Causes the Accelerated Loss of Cartilage during Fracture Repair which is Reversed by Insulin Treatment. BONE (In Press).
  173. Morgan, E. F., Mason, Z. D., Chien, K. B., Pfeiffer, A.,J., Barnes, G. L., Einhorn, T. A., and Gerstenfeld, L. C.: Microstructured Tomography Assessment of Fracture Healing: Relationships among Callus Structure, Composition, and Mechanical Function: BONE (In Press).
  174. Gerstenfeld, L. C., Sacks, D. J., Pelis, M., Mason, Z. D., Graves, D. T., Barrero, M., Ominsky, M. S., Kostenuik, P. J., Morgan, E. F., Einhorn, T. A.: Comparison of Effects of the Bisphosphonate Alendronate Versus the RANKL Inhibitor Denosumab on Murine Fracture Healing. J. BONE MINER. RES. (In Press).
  175. Saleh, K., J., Quick, J., C., Sime, W., E., Novicoff, W., M., and Einhorn, T., A.: Recognizing and Preventing Burnout among Orthopaedic Leaders. CLIN. ORTHOP. RELAT. RES., 467:558-65, 2009.
  176. Wan, C., Gilbert, S. R., Cao, X. M., Shen, X., Ramaswamy, G., Jacobsen, K. A., Alaql, Z. S., Gerstenfeld, L. C., Einhorn, T. A. , Eberhardt, A. A., Deng, L., Guldberg, R. E., and Clemens, T. L.: Role of Hypoxia Inducible Factor-1 Alpha in Bone Regeneration. J. MUSCULOSKELET NEURONAL INTERACT., 8:323-324, 2009.
  177. Kooistra, B., Dijkman, B., Einhorn, T. A. Bhandari, M.: How to Design a Good Case Series. J BONE JOINT SURG., 91A:Suppl 3:21-26, 2009.
  178. Hunter, D. J., Gerstenfeld, L., Bishop, G., Davis, A. D., Mason, Z. D., Einhorn, T. A. , Maciewicz, R. A., Newham, P., Foster, M., Jackson, S., and Morgan, E. F.: Bone Marrow Lesions from Osteoarthritic Knees are Characterized by Sclerotic Bone that is Less Well Mineralized. ARTHRITIS RES. THER. (In Press).
  179. Palomares, K. T., Gleason, R. E., Mason, Z. D., Cullinane, D. M., Einhorn, T. A., Gerstenfeld, L. C., and Morgan, E. F.: Mechanical Stimulation Alters Tissue Differentiation and Molecular Expression during Bone Healing. J. ORTHOP. RES. (In Press).
  180. Bais, M. V., Wigner, N., Young, M., Toholka, R., Graves, D. T., Morgan, E. F., Gerstenfeld, L., C., and Einhorn, T., A.: BMP2 Is Essential for Post Natal Osteogenesis but Not for Recruitment of Osteogenic Stem Cells. BONE (In Press).

TEXTBOOKS:

  1. Orthopaedic Basic Science: Foundations of Clinical Practice. 3rd Edition. T.A. Einhorn, J.A. Buckwalter, and R. J. O’Keefe, Eds., Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 2007.
  2. Orthopaedic Basic Science: The Biology and Biomechanics of the Musculoskeletal System. 2nd Edition. J.A. Buckwalter, T.A. Einhorn, and S.R. Simon, Eds., Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 2000.
  3. Orthopaedic Surgery Essentials: P. Tornetta, III and T. A. Einhorn, Series Eds., Philadelphia, PA., LIPPINCOTT WILLI WILLIAMS & WILKINS, 2003.
  4. Bone Tissue Engineering: J. O. Hollinger, T. A. Einhorn, B. Doll and C. Sfeir Eds., Boca Raton, Fla. CRC PRESS, 2004.

BOOK CHAPTERS:

  1. Einhorn, T.A., Beyer, M.M., and Devlin, V.J.:Bone Integrity in Experimental Diabetes. In The Diabetic Renal Retinal Syndrome III:Treatment. Edited by Eli A. Friedman, M.D. and Francis A. L'Esperance, Jr., M.D., New York, GRUNE & STRATTON PUBLISHERS, 1985, pp. 131 137.
  2. Einhorn, T.A.: Preservation of the Compromised Foot in Diabetic Nephropathy. In Diabetic Nephropathy. Edited by Eli A. Friedman,M.D. and Charles M. Peterson, M.D., Boston, KLUMER NIJHOFF PUBLISHERS, 1986, pp. 179 186.
  3. Einhorn, T.A.: Dietary Protein and Bone Calcium Metabolism. In Nutrition and Bone Development. Edited by David J. Simmons, Ph.D., New York, OXFORD UNIVERSITY PRESS., 1989, pp. 223-236.
  4. Einhorn, T.A.: Metabolic Bone Disease of the Lumbar Spine. In The Lumbar Spine: Current Concepts. Edited by Yizhar Floman, M.D.,Rockville, Md., ASPEN PUBLISHERS, INC., 1990, pp. 749-777.
  5. Einhorn, T.A., Klein, M.J., and Lewis, M.M.: Orthopaedic Problems. In The Merck Manual of Geriatrics. Edited by William B. Abrams, M.D. and Robert Berkow, M.D., Rahway, N.J., MERCK and CO., INC., 1990, pp 755-760.
  6. Bromson, M.S., and Einhorn, T.A.:Metabolic Mimickers of Tumor.In: Musculoskeletal Oncology:A Multidisciplinary Approach.Edited by M.M. Lewis, Philadelphia, PA, W.B. SAUNDERS CO., 1991, pp 401-409.
  7. Horowitz, M.C., Jilka, R.L., and Einhorn, T.A.:Effect of Endotoxin (Lipopolysaccharide) on Bone Cell Function, Bone Allograft Incorporation and Fracture Repair.In:Musculoskeletal Infection.Edited by J.L. Esterhai, Jr., A.G. Gristina, and R. Poss, Park Ridge, Illinois, AM. ACAD. ORTHOP. SURG., 1992, pp. 271-289.
  8. Einhorn, T.A.:Bone Metabolism and Metabolic Bone Disease.In:Orthopaedic Knowledge Update 4 Home Study Syllabus.Edited by J.W. Frymoyer, Park Ridge, Illinois, AM. ACAD. ORTHOP. SURG., 1993, pp. 69-88.
  9. Kaplan, F.S., Hayes, W.C., Keaveny, T.M., Boskey, A.L., Einhorn, T.A., and Iannotti, J.P.:Form and Function of Bone.In:Orthopaedic Basic Science.Edited by S.R. Simon, Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 1994, pp. 127-184.
  10. Ostrum, R.F., Chao, E.Y.S., Bassett, C.A.L., Brighton, C.T., Einhorn, T.A., Lucas, T.S., Aro, H.T., and Spector, M.:Bone Injury, Regeneration, and Repair.In:Orthopaedic Basic Science.Edited by S.R. Simon, Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 1994, pp. 277-323.
  11. Einhorn, T.A., Lucas, T.S., Molinari, R.W., Flancbaum, L., Burge, J.C., Esterhai, J.L., Jr., Springfield, D.S., and Bone, L.B.:Conditions Affecting Orthopaedic Surgical Practice.In:Orthopaedic Basic Science.Edited by S.R. Simon, Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 1994, pp. 487-517.
  12. Einhorn, T.A.:The Roles of Osteoporosis and Falls in Hip Fractures in the Elderly.In:Prevention of Falls and Hip Fractures in the Elderly.Edited by D.F. Apple and W.C. Hayes.Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 1994, pp. 19-32.
  13. Einhorn, T.A.:Enhancement of Fracture Healing by Molecular or Physical Means:An Overview.In:Bone Formation and Repair.Edited by C.T. Brighton, G. Friedlaender, and J.M. Lane, Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 1994, pp. 223-238.
  14. Einhorn, T.A.:Enhancement of Fracture Healing.In:Instructional Course Lectures, Vol. 45, Edited by D.J. Pritchard, Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 1996, pp. 401-416.
  15. Buckwalter, J.A., Einhorn, T.A., Bolander, M.E., and Cruess, R.L.:Healing of the Musculoskeletal Tissues.In:Rockwood and Green's Fractures in Adults.Fourth edition, edited by C.A. Rockwood, Jr., D.P. Green, R.W. Bucholz, and J.D. Heckman, Philadelphia, LIPPINCOTT-RAVEN, 1996, pp. 261-304.
  16. Einhorn, T.A.:Bone Metabolism and Metabolic Bone Disease. In:Orthopaedic Knowledge Update 5 Home Study Syllabus. Edited by J. R. Kasser, Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 1996, PP. 199-132.
  17. Einhorn, T.A.:The Bone Organ System:Form and Function. In:Osteoporosis.Edited by R. Marcus, D. Feldman, and J. Kelsey, San Diego, ACADEMIC PRESS, 1996, pp. 3-22.
  18. Lucas, T.S., and Einhorn, T.A.: Metabolic Disorders of the Spine. In:The Practice of Neurosurgery. Edited by G.T. Tindall, P.R. Cooper, and D.L. Barrow. Baltimore, WILLIAMS AND WILKINS, 1996, pp. 2377-2391.
  19. Einhorn, T.A.: Orthopedic Complications of Osteoporosis. In:Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Third Edition, Edited by M.J. Flavus, Philadelphia, LIPPINCOTT-RAVEN, 1996, pp. 293-299.
  20. Einhorn, T.A.: Biomechanics of Bone. In:Principles of Bone Biology, Edited by J.P. Bilezekian, L.G. Raisz, and G.A. Rodan, San Diego, ACADEMIC PRESS, 1996, pp. 25-37.
  21. Styles, S.J., and Einhorn, T.A.: Fracture Healing and Responses to Skeletal Injury. In: Principles of Orthopaedic Practice.2nd Edition. Edited by R. Dee, L.C. Hurst, M.A. Gruber, and S. Kottmeier, New York, MCGRAW-HILL, 1997, pp. 71-78.
  22. Einhorn, T.A. and Trippel, S.B.: Growth Factor Treatment of Fractures. In: Instructional Course Lectures, Vol. 46, Edited by Dempsey S. Springfield, Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 1997, pp. 483-486.
  23. Hall, J.C., and Einhorn, T.A.: Metabolic Bone Disease of the Adult Spine. In: The Adult Spine: Principles and Practice. Edited by J.W. Frymoyer et al., Philadelphia, LIPPINCOTT-RAVEN, 1997, pp. 783-802.
  24. Mirsky, E.C., and Einhorn, T.A.: Metabolic Bone Disease. In: The Adult Hip. Edited by J.J. Callaghan, A.G. Rosenberg and H.E. Rubash, Philadelphia, LIPPINCOTT-RAVEN, 1998, pp. 507-526.
  25. Cavallo, R.J., and Einhorn, T.A.: Enhancement of Skeletal Repair. In: Skeletal Trauma. Edited by B.D. Browner, J.B. Jupiter, A.M. Levine, and P.G. Trafton, Philadelphia, WB SAUNDERS, 1998, pp. 703-718.
  26. Einhorn, T.A. and Gill, S. S.: Bone Metabolism and Metabolic Bone Disease. In:Orthopaedic Knowledge Update 6 Home Study Syllabus. Edited by J. H. Beaty, Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 1999, pp. 149-165.
  27. Einhorn, T.A.: Orthopedic Complications of Osteoporosis. In: Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Fourth Edition, Edited by M.J. Favors, Philadelphia, LIPPINCOTT WILLIAMS & WILKINS, 1999, pp. 307-313.
  28. Morris, C.D. and Einhorn, T.A.: Orthopaedic Pharmacology. In: Orthopaedic Basic Science, 2nd Edition, Edited by J. A. Buckwalter, T. A. Einhorn and S. R. Simon, Rosement, Illinois, AM. ACAD. ORTHOP. SURG., 2000, pp. 217-237.
  29. Morris, C.D., W.R. Creevy and Einhorn, T.A.: Pulmonary Distress and Thromboembolic Conditions Affecting Orthopaedic Surgical Practice. In: Orthopaedic Basic Science, 2nd Edition, Edited by J. A. Buckwalter, T. A. Einhorn and S. R. Simon, Rosement, Illinois, AM. ACAD. ORTHOP. SURG., 2000, pp. 307-316.
  30. M.P.G. Bostrom, A. Boskey, J.K. Kaufman and Einhorn, T.A.: Form and Function of Bone. In: Orthopaedic Basic Science, 2nd Edition, Edited by J.A. Buckwalter, T.A. Einhorn and S.R. Simon, Rosement, Illinois, AM. ACAD. ORTHOP. SURG., 2000, pp. 319-369.
  31. S.M. Day, R.F. Ostrum, E.Y.S. Chao, C.T. Rubin, H.T. Aro and Einhorn, T.A.: Bone Injury, Regeneration and Repair. In: Orthopaedic Basic Science, 2nd Edition, Edited by J. A. Buckwalter, T. A. Einhorn and S. R. Simon, Rosement, Illinois, AM. ACAD. ORTHOP. SURG., 2000, pp. 371-399.
  32. Beasley, L. S., and Einhorn, T. A.: The Role of Growth Factors in Fracture Healing. In: Skeletal Growth Factors. Edited by E. Canalis, Philadelphia, LIPPINCOTT WILLIAMS & WILKINS, 2000 pp. 311-322.
  33. Dewire, P. and Einhorn, T. A.: The Joint as an Organ. In: Osteoarthritis: Medical/Surgical Management, 3rd Edition, Edited by R. W. Moskowitz, D. S. Howell, R. D. Altman, J. A. Buckwalter and V. M. Goldberg, Philadelphia, W. B. SAUNDERS, 2001, pp. 49-68.
  34. Lee, C. A and Einhorn, T.A.:The Bone Organ System:Form and Function. In:Osteoporosis. Second Edition, Edited by R. Marcus, D. Feldman, and J. Kelsey, San Diego, ACADEMIC PRESS, 2001, pp. 3-20.
  35. Buckwalter, J.A., Einhorn, T.A and Marsh, L. J.: Bone and Joint Healing. In:Rockwood and Green's Fractures in Adults. Fifth edition, edited by R.W. Bucholz, and J.D. Heckman, Philadelphia, LIPPINCOTT WILLIAMS & WILKINS, 2001, pp. 245-271.
  36. Cullinane, D. M. and Einhorn, T.A.: Biomechanics of Bone. In:Principles of Bone Biology, Edited by J.P. Bilezekian, L.G. Raisz, and G.A. Rodan, San Diego, ACADEMIC PRESS, 2002, pp. 17-32.
  37. Greenfield, E. M. and Einhorn, T. A.: Calcium Homeostasis. In: Orthopaedics, Edited by R. H. Fitzgerald, H. Kaufer and A. L. Malkani, St. Louis, MOSBY, INC., 2002, pp. 195-200.
  38. Moucha C. S., and Einhorn, T.A.: Enhancement of Skeletal Repair. In: Skeletal Trauma. Edited by B.D. Browner, J.B. Jupiter, A.M. Levine, and P.G. Trafton, Philadelphia, WB SAUNDERS, 2003, pp. 639-659.
  39. Einhorn, T.A.:The Structural Properties of Normal and Osteoporotic Bone. In:Instructional Course Lectures, Vol. 52, Edited by D.C. Ferlic, Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 2003, pp. 533-539.
  40. Bono, C. M. and Einhorn, T.A.: Orthopedic Complications of Osteoporosis. In: Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Fifth Edition, Edited by M.J. Flavus, Philadelphia, AM. SOC. BONE MINER. RES., 2003, pp. 388-398.
  41. Gill, S. S. and Einhorn, T. A.: Metabolic Bone Disease of the Adult and Pediatric Spine. In: The Adult and Pediatric Spine. Third Edition, edited by J. W. Frymoyer and S. W. Wiesel, Philadelphia, LIPPINCOTT WILLIAMS & WILKINS, 2004, pp. 121-139.
  42. Einhorn, T. A.: Tissue Engineering of Fracture Repair. In: Tissue Engineering in Musculoskeletal Clincal Practice. Edited by L. J Sandell and A. J. Grodzinsky, Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 2004, pp. 107-114.
  43. Kakar, S, and Einhorn, T. A.: Importance of Nutrition in Fracture Healing. In: Nutrition and Bone Health. Edited by M. F. Holick and B. D. Dawson-Hughes, Totowa, N. J., HUMANA PRESS, 2004, pp. 85-103.
  44. Kakar, S, and Einhorn, T. A.: Tissue Engineering of Bone. In: Bone Tissue Engineering. Edited by J. O. Hollinger, T. A. Einhorn, B.A. Doll and C. Sfeir, Boca Raton, Fla., CRC PRESS, 2004, pp. 277-302.
  45. Moucha, C.S., and Einhorn, T. A.: Bone Morphogenetic Proteins and Other Growth Factors to Enhance Healing and the Treatment of Nonunions. In: Bone Regeneration and Repair: Biology and Clinical Applications. Edited by J. R. Lieberman and G. E. Friedlaender, Totowa, N. J., HUMANA PRESS, 2005, pp. 169-194.
  46. Tsiridis, E., Kakar, S., and Einhorn, T. A.: Fracture Healing and Bone Grafting. Edited by J. A. Elstrom, W. W. Virkus, and A. M. Pankovich, New York, N.Y., MCGRAW-HILL, 2005, pp. 49-61
  47. Kakar, S, and Einhorn, T. A.: Tissue Engineering of Bone. In: An Introduction to Biomaterials. Edited by S. A. Guelcher and J. O. Hollinger, Boca Raton, Fla., CRC PRESS, 2006, pp. 417-440.
  48. Buckwalter, J.A., Einhorn, T.A and Marsh, L. J.: Bone and Joint Healing. In: Rockwood and Green's Fractures in Adults. Sixth edition, edited by R.W. Bucholz, J.D. Heckman, and C. Court-Brown, Philadelphia, LIPPINCOTT WILLIAMS & WILKINS, 2006, pp. 297- 311.
  49. Kakar, S. Tsiridis, E., and Einhorn, T.A : Bone Grafting and Enhancement of Fracture Repair. In:Rockwood and Green's Fractures in Adults. Sixth edition, edited by R.W. Bucholz, J.D. Heckman, and C. Court-Brown, Philadelphia, LIPPINCOTT WILLIAMS & WILKINS, 2006, pp. 313 - 330.
  50. Gerstenfeld, L. C, and Einhorn, T. A.: Osteoporosis and Bone Physiology. In: Rothman-Simeone: The Spine. Fifth Edition. Edited by H. N. Herkowitz, S.R. Garfin, F.J. Eismont, G.R. Bell, and R.A. Balderston, Philadelphia, SAUNDERS ELSEVIER, 2006, pp. 108-121.
  51. Bono, C. M. and Einhorn, T.A.: Fracture Healing: The Biology of Bone Repair and Regeneration.In: Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Sixth Edition, Washington, D.C., AM. SOC. BONE MINER. RES., 2006, pp. 42-48.
  52. Bonenberger, E. G., and Einhorn, T.A.: Metabolic Bone Diseases. In: The Adult Hip. Edited by J.J. Callaghan, A.G. Rosenberg and H.E. Rubash, Philadelphia, LIPPINCOTT-RAVEN, 2007, pp. 514-533.
  53. Gerstenfeld, L. C., Edgar, C. M., Kakar, S., Jacobsen, K. A., and Einhorn, T. A. Osteogenic Growth Factors and Cytokines and Their Role in Bone Repair. In: Engineering of Functional Skeletal Tissues (Series: Topics in Bone Biology , Vol. 3). Edited by Bronner, Felix; Farach-Carson, Mary C.; Mikos, Antonios G., London, SPRINGER-VERLAG, 2007, pp 17-457.
  54. Einhorn, T. A. : Metabolic Bone Disease, In: Orthopaedic Basic Science: Foundations of Clinical Practice. 3rd Edition., T.A. Einhorn, J.A. Buckwalter, and R. J. O’Keefe, Eds., Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 2007, pp. 415-456.
  55. Morgan, E. F., Barnes, G. L., and Einhorn, T.A.:The Bone Organ System: Form and Function. In: Osteoporosis. Third Edition, Edited by R. Marcus, D. Feldman, D. A. Nelson and C. J. Rosen, San Diego, Burlington, London, ELSEVIER ACADEMIC PRESS, 2008, pp. 3-25.
  56. Covey, D. C., Aaron, R. K., Born, C. T., Calhoun, J. H., Einhorn, T.A, Hayda, R. A., Levin., L. S., Mazurek, M. T., Murray, C. K., Powell, E. T., Schwartz, E. M., and Wenke, J., C.: Orthopaedic War Injuries: From Casualty Care to Definitive Treatment: A Current Review of Clinical Advances, Basic Science, and Research Opportunites. In: Instructional Course Lectures, Vol. 57, Edited by P. J. Duwelius and F. M. Azar, Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 2008, pp. 65-86.
  57. Morgan, E. F., and Einhorn, T.A.: Biomechanics of Fracture Healing. In: Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, Seventh Edition, Washington, D.C., AM. SOC. BONE MINER. RES., 2006, pp. 65-69.
  58. Kakar, S., and Einhorn, T.A.: Biology and Enhancement of Skeletal Repair. In: Skeletal Trauma. Edited by B.D. Browner, J.B. Jupiter, A.M. Levine, P.G. Trafton, and C. Krettek. Philadelphia, SAUNDERS ELSEVIER, 2008, pp. 33 - 50.
  59. Austin, M. S., Abdul-Hadi, O., Parvizi, J., Viscusi, E. R., and Einhorn, T.A,: Cyclooxygenase-2 Inhibitors and Other Nonsteroidal Anti-inflammatory Drugs in the Treatment of Musculoskeletal Conditions. In: Instructional Course Lectures, Vol. 58, Edited by F. M. Azar and M. I. O’Connor, Rosemont, Illinois, AM. ACAD. ORTHOP. SURG., 2009, pp. 759 - 768.

INVITED ARTICLES, MONOGRAPHS AND OTHER PUBLICATIONS:

  1. Einhorn, T.A., Hirschman, A., Gordon, S.L., Avitable, M.J., and Carty, R.P.: Enzymes Associated with Matrix Vesicles Isolated from Osteoarthritic Cartilage. In: Cell Mediated Calcification and Matrix Vesicles. Edited by S. Yousuf Ali. Amsterdam, ELSEVIER SCIENCEPUBLISHERS, 1986, pp. 359 364.
  2. Einhorn, T.A., and Vigorita, V.J.: Unique Histology the Fracture Callus in a Sodium Fluoride Treated Osteoporotic Patient with Hip Fracture. In:"Osteoporosis 1987".Edited by C. Christiansen and B.J. Riis, Copenhagen, Denmark, OSTEOPRESS ApS, 1987 pp.262 265.
  3. Einhorn, T.A.: Osteoporosis and Exercise. OSTEOPATHIC MEDICAL NEWS, 5:53 62, 1988.
  4. Einhorn, T.A.: Metabolic Bone Disease: Diagnosis and Treatment. HOSPIMEDICA, 6:45 52, 1988.
  5. Einhorn, T.A.: Hip Fractures in the Elderly. RESIDENT AND STAFF PHYSICIAN, 34:97-113, 1988.
  6. Einhorn, T.A.: Biomechanical Properties of Bone. TRIANGLE, 27:27-36, 1988.
  7. Einhorn, T.A., Levine, B., and Michel, P.: Nutrition and Bone. ORTHOP. CLIN. NORTH AMERICA, 21:43-50, 1990.
  8. Einhorn, T.A.: Mechanisms of Fracture Healing. HOSP. PRACT. 26 (Suppl 1):41-45, 1991.
  9. Einhorn, T.A., Azria, M., and Goldstein, S.A.:Bone Fragility: The Biomechanics of Normal and Pathologic Bone. SANDOZ PHARMA LTD.MONOGRAPH, 1992.
  10. Einhorn, T.A.: Bone Remodeling in Fracture Repair. TRIANGLE, 31:89-98, 1992.
  11. Einhorn, T.A.: Managing Orthopaedic Manifestations of Gaucher Disease. Pawling, N.Y., Cadeuceus Med. Publ, 1993.
  12. Silver, J.J., Majeska, R.J., and Einhorn, T.A.: An Update on Bone Cell Biology. CURR. OPIN. ORTHOP., 5:50-59, 1994.
  13. Einhorn, T.A.: Use of Estrogen for Osteoporosis. AAOS BULLETIN, 42:10-12, 1994.
  14. Kagel EM, Majeska RJ, Einhorn TA. : Effects of Diabetes and Steroids on Fracture Healing.CURR. OPIN. ORTHOP., 6:7-13, 1995.
  15. Einhorn, T.A.:Point of View: Pitfalls in the Measurement of Bone Mineral Density by Dual Energy X-ray Absorptiometry.SPINE, 21:87-91, 1996.
  16. Kagel, E.M., and Einhorn, T. A. : Alterations of Fracture Healing in the Diabetic Condition.IOWA ORTHOP. J., 16:147-152, 1996.
  17. Einhorn, T.A.:Point of View: Regional Variation in Vertebral Bone Density and Trabecular Architecture are Influenced by Osteoarthritic Change and Osteoporosis. SPINE, 22:2401-2402, 1997.
  18. Einhorn, T. A.: Foreward. In: Magnetic Resonance Imaging of Orthopedic Trauma. Edited by Stephen J. Eustace, Philadelphia, Lippincott Williams & Wilkins, 1999, p. xiii.
  19. Bostrum, P.G.M., Saleh, K.J., and Einhorn, T. A.: Osteoinductive Growth Factors in Preclinical Fracture and Long Bone Defects. In: The Orthopaedic Clinics of North America - "Bone Grafting and Bone Graft Substitutes". Edited by S.D. Boden and S. Stevenson, Philadelphia, W. B. Saunders, 1999, pp. 647-658.
  20. Einhorn, T. A.: Commentary - Sheep Model for Fracture Treatment in Osteoporotic Bone: A Pilot Study About Different Induction Regimens. J. ORTHOP. TRAUMA, 565-566, 1999.
  21. Einhorn, T. A. and Nielsen, G. P.: Case Records of the Massachusetts General Hospital: A 26-Year-Old Man with a Mass in the Knee. N. ENGL. J. MED., 344:124-131, 2001.
  22. Einhorn, T. A.: Commentary: "Osteoporosis: The Missed Opportunity of Orthopaedics". J.BONE JOINT SURG., 83A: http://www.jbjs.org, 2001.
  23. Cho, T-J, Gerstenfeld, L.C., Barnes, G. L., and Einhorn TA. : Cytokines in Fracture Healing. CURR. OPIN. ORTHOP., 12:403-408, 2001.
  24. Einhorn, T. A.: Commentary: "No Need to Believe in Magic". J.BONE JOINT SURG., 83A: http://www.jbjs.org, 2001.
  25. Einhorn, T. A.: Commentary: "Improvement in the Undertreatment of Osteoporosis Following Hip Fracture". J.BONE JOINT SURG., 84A: http://www.jbjs.org, 2002.
  26. Einhorn, T. A.: Use of Cox-2 Inhibitors in Patients with Fractures: Is There a Trade-off Between Pain Relief and Healing? AAOS BULLETIN 50:43-44, 2002.
  27. Einhorn, T. A.: Orthopedic Gene Therapy: Building Bones. GENE THER., 10:529, 2003.
  28. Einhorn, T. A.: Commentary: "Colles Fracture, Spinal Fracture, and Subsequent Risk of Hip Fracture in Men and Women. A Meta-Analysis". J.BONE JOINT SURG., 85A: http://www.jbjs.org, 2003.
  29. Einhorn, T. A.: Commentary: "Percutaneous Injection of Recombinant Human Bone Morphogenetic Protein-2 in a Calcium Phosphste Paste Accelerates Healing of a Canine Tibial Osteotomy". J.BONE JOINT SURG., 86A: http://www.jbjs.org, 2004.
  30. Einhorn, T. A. and J. L. Fitch: Commentary: "Osteoinductivity of Commercially Available Demineralized Bone Matrix Preparations in a Spine Fusion Model". J.BONE JOINT SURG., 86A: http://www.jbjs.org, 2004.
  31. Einhorn, T.A.: Point of View: "Genetically Modified Human-Derived Bone Marrow Cells for Posterolateral Lumbar Fusion in Athymic Rats: Beyond Conventional Autologous Bone Grafting". SPINE, 30:289-290, 2005.
  32. Einhorn, T. A.: Commentary: "The Use of Alendronate to Prevent Early Collapse of the Femoral Head in Patients with Nontraumatic Osteonecrosis: A Randomized Clinical Study". J.BONE JOINT SURG., 87A: http://www.jbjs.org, 2005.
  33. Kakar, S. and Einhorn, T. A.: The Role of Bone Morphogenetic Proteins in Skeletal Repair. In: Bone Grafts and Bone Graft Substitutes, edited by G. E. Friedlaender, H. J. Mankin, V. M. Goldberg, Rosemont, Ill, AM. ACAD. ORTHOP. SURG., 2006, pp. 21-32.
  34. Einhorn, T.A.: Point of View: "Intervariability and Intravariability of Bone Morphogenetic Proteins in Commercially Available Demineralized Bone Matrix Products". SPINE, 31:1307-1308, 2006.
  35. Einhorn, T. A.: Commentary: "Recombinant Human Bone Morphogenetic Protein-2 in Open Tibial Fractures: A Subgroup Analysis of Data Combined from Two Prospective Randomized Studies". J.BONE JOINT SURG., 88A: http://www.jbjs.org, 2006.
  36. Einhorn, T. A. : Pharmaceutical Agents for the Treatment of Osteoporosis. COA BULLETIN ACO, 73:21-23, 2006.
  37. Barnes, G.L. and Einhorn T.A.: Enhancement of Fracture Healing with Parathyroid Hormone. CLIN. REV. BONE MINER METAB., 4:269-276, 2006.
  38. Einhorn, T. A.: Commentary: "Dose and Time-dependent Effects of Cyclooxygenase-2 Inhibition on Fracture-Healing". J.BONE JOINT SURG., 89A: http://www.jbjs.org, 2007.
  39. Axelrad, T. W., Einhorn, T. A.: New Biotechnologies for the Stimulation of Bone Repair. G.I.O.T., 33(Suppl.1):S262-S266, 2007.
  40. Einhorn, T. A.: Commentary: "Proximal Humeral Fracture as a Risk Factor for Subsequent Hip Fractures". J.BONE JOINT SURG., 91A: http://www.jbjs.org, 2009.

EDITORIALS:

  1. Einhorn, T.A.:Editorial: Sharing Our Knowledge: The Importance of International Exchange of Ideas in Orthopaedic Research.J. ORTHOP. RES., 14:341-342, 1996.
  2. Einhorn, T.A.:Editorial: Re-Engineering the Tree of Knowledge:Orthopaedic Research After the Fall.J. ORTHOP. RES., 14:511-512, 1996.
  3. Einhorn, T.A.,, Burstein, A. H., and Cowell, H.R.:Editorial: Human Experimentation.J. BONE JOINT SURG., 79A:959-960, 1997.
  4. Einhorn, T.A.:Editorial:J. ORTHOP. TRAUMA., 11:243, 1997.
  5. Einhorn, T.A.:Editorial: One of Nature's Best Kept Secrets. J. BONE MINER. RES., 13:10-12, 1998.
  6. Einhorn, T.A. and Lane, J.M.: Editorial Comment. Fracture Healing Enhancement. CLIN.ORTHOP., 355S: S2-S3, 1998.
  7. Einhorn, T. A.: Editorial: Vertebroplasty: An Opportunity to Do Something Really Good for Patients. SPINE, 25:1051-1052, 2000.
  8. Einhorn, T. A.: Editorial: Brain, Bone, and Body Mass: Fat is Beautiful Again. J. BONE JOINT SURG., 83A:1782, 2001.
  9. Einhorn, T. A.: Do Inhibitors of Cyclooxygenase-2 Impair Bone Healing? J. BONE MINER. RES., 17:977-978, 2002.
  10. Einhorn, T. A.: "If It Feels Good, Do It": Use of Glucosamine to Prevent the Progression of Osteoarthritis in Postmenopausal Women. MENOPAUSE 11:134-135, 2004.
  11. Jarvinen TL, Sievanen H, Jokihaara J, Einhorn TA.: Editorial: Revival of Bone Strength: The Bottom Line. J BONE MINER. RES., 20:717-20, 2005.
  12. Wright, J. G., Einhorn, T. A., and Heckman, J. D.: Grades of Recommendation. J. BONE JOINT SURG., 87A: 1909-1910, 2005.
  13. Giannoudis, P. V., Einhorn, T. A., and Marsh, D.: Fracture Healing: A Harmony of Optimal Biology and Optimal Fixation. INJURY 38 Suppl 4:S1-2.2007.

BOOK REVIEWS:

  1. Osteosclerosis, Hyperostosis and Related Disorders. Boy Frame, Mahalakshmi Honasoge, Sambasiva R. Kottamasu, New York, Elsevier, 1987.J. BONE JOINT SURG. 70A:158, 1988.
  2. Osteoporosis:Papers Presented During the Ninth International Conference, Nice, France, October 25 to November 1, 1986.D.V. Cohn and T.J. Martin, Editors. New York, Elsevier 1987.J. BONE JOINT SURG. 70A:1438, 1988.
  3. The Technique of Total Hip Arthroplasty.Hugh A. Cameron, St. Louis, Mosby, 1992.N. ENGL. J. MED., 328:591-592, 1993.
  4. Bone Morphogenetic Proteins:Biology, Biochemistry and Reconstructive Surgery. T. Sam Lindholm. Austin, Texas, R.G. Lander Company and Academic Press, 1996, J. BONE JOINT SURG., 79A:318, 1997.
  5. Bone Graft Substitutes. Cato T. Laurencin, Editor. Rosemont, Am Soc. Testing Mater. and Am. Acad. Orthop. Surg., J. BONE JOINT SURG., 86A:1350-1351, 2004
  6. Bone Regeneration and Repair: Biology and Clinical Applications. Jay R. Lieberman and Gary E. Friedlaender, Editors. Totowa, N. J., Humana Press., J. BONE JOINT SURG., 88A:469-470, 2006.

ABSTRACTS:

Available On Request

Dr. Thomas A. Einhorn's Specialties

  • Adult Stem Cell Breakthrough Surgery for Avascular Necrosis of the Hip
  • Hip Replacement
  • Knee Replacement
  • Adult Stem Cell Breakthrough Surgery for Nonunion Fractures

Unlike osteoarthritis, Avascular Necrosis of the Hip tends to affect a young population from 20 to 60 years of age, for whom a total hip replacement is a sub-optimal solution.

Until very recently, the most common treatment of Avascular Necrosis of the femoral head has been total hip replacement, which is often a sub-optimal solution for patients under 50 years of age due to possible activity restrictions and the fact that a synthetic hip joint will wear out with time. Dr. Einhorn offers young patients a viable, safe alternative to hip replacement surgery with adult stem cell orthopaedic surgery.

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Stem Cells Heal Fractures

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