| NAME: |
Thomas Alfred Einhorn, M.D. |
| CITIZENSHIP: |
United States of America |
| OFFICE ADDRESS: |
Department of Orthopaedic Surgery
Boston Medical Center - DOB Suite 808
720 Harrison Avenue
Boston, Massachusetts 02118-2393 |
| TELEPHONE: |
(617) 638-8435 |
| FAX: |
(617) 638-8493 |
| E-MAIL: |
Thomas.Einhorn@BMC.ORG |
| Current Position: |
Chairman
Department of Orthopaedic Surgery
Boston University School of Medicine
Chief, Orthopaedic Surgery
Boston Medical Center
|
| EDUCATION: |
Cornell University Medical College
New York, New York
Degree: M.D., 1976
Rutgers University
New Brunswick, New Jersey
|
| Degree: |
A.B., 1972 |
| ACADEMIC HONORS AND AWARDS: |
Phi Beta Kappa, 1972
Rutgers University
S. Oakley Van Der Poel Chemistry Award, 1972
Rutgers University
Henry Rutgers Scholar, 1971-1972
Rutgers University
Philip D. Wilson Award, 1982
Hospital for Special Surgery
American British Canadian Traveling Fellowship, 1989
American Orthopaedic Association
M.R. Urist Award, 1997
Portland Bone Symposium
Bentham Award, 1998
Boston University School of Medicine
Kappa Delta Award, 1999
American Academy of Orthopaedic Surgeons
Marshall Schiff Award, 2000
American College of Rheumatology
Marshall R. Urist Award, 2002
Orthopaedic Research Society
Dr. Marian Ropes - Physician Achievement Award, 2006
Arthritis Foundation
Alfred R. Shands, Jr., M.D. Award, 2008
Orthopaedic Research Society
American Orthopaedic Association
|
| PEER RECOGNITION: |
Best Doctors, 1991 - Present
Castle Connolly America's Top Doctors, 1995 - Present
|
| CERTIFICATIONS: |
National Board of Medical Examiners
July 1, 1977
American Board of Orthopaedic Surgery
July 27, 1984
Recertification - July 25, 1997
|
| MEDICAL LICENSES: |
New York: 131052-1977
Massachusetts: 154139-1997
|
| POST GRADUATE TRAINING: |
July 1, 1981 - June 30, 1982
Fellow, Metabolic Bone Disease and Orthopaedic Research
The Hospital for Special Surgery
New York, New York
July 1, 1978 - June 30, 1981
Resident, Orthopaedic Surgery
St. Luke's - Roosevelt Hospital Center
Columbia University
New York, New York
July 1, 1977 - June 30, 1978
Resident, General Surgery
St. Vincent's Hospital & Medical Center
New York, New York
June 18, 1976 - June 18, 1977
Intern, General Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
|
| ACADEMIC APPOINTMENTS: |
May 1, 1997 - Present
Professor and Chairman
Department of Orthopaedic Surgery
Boston University School of Medicine
Boston, Massachusetts
February 1, 2005 - Present
Professor
Department of Biomedical Engineering
Boston University College of Engineering
Boston, Massachusetts
September 14, 1999 - Present
Research Professor
Department of Biochemistry
Boston University School of Medicine
Boston, Massachusetts
January 1, 1992 - April 30, 1997
Professor of Orthopaedics
Director of Orthopaedic Research
Mount Sinai School of Medicine
City University of New York
New York, New York
July 1, 1988 - December 31, 1991
Associate Professor or Orthopaedics
Director of Orthopaedic Research
Mount Sinai School of Medicine
City University of New York
New York, New York
July 1, 1982 - April 30, 1997
Visiting Scientist, Research Division
The Hospital for Special Surgery
New York, New York
December 1, 1986 - June 30, 1988
Assistant Professor of Orthopaedics
Mount Sinai School of Medicine
City University of New York
New York, New York
July 1, 1982 - November 30, 1986
Assistant Professor of Orthopaedic Surgery
State University of New York
Health Science Center of Brooklyn
Brooklyn, New York
|
| HOSPITAL APPOINTMENTS: |
May 1, 1997 - Present
Chief of Orthopaedic Surgery
Boston Medical Center
Boston, Massachusetts
January 1, 1992 - April 30, 1997
Attending Orthopaedic Surgeon
The Mount Sinai Hospital
New York, New York
July 1, 1988 - December 31, 1999
Associate Attending Orthopaedic Surgeon
The Mount Sinai Hospital
New York, New York
December 1, 1986 - June 30, 1988
Assistant Attending Orthopaedic Surgeon
The Mount Sinai Hospital
New York, New York
July 1, 1982 - November 30, 1986
Assistant Attending Orthopaedic Surgeon
State University Hospital
Brooklyn, New York
July 1, 1982 - November 30, 1986
Assistant Attending Orthopaedic Surgeon
Kings County Hospital
Brooklyn, New York
June 24, 1982 - November 30, 1986
Staff Physician
Veterans Administration Medical Center
Brooklyn, New York
July 1, 1984 - November 30, 1986
Assistant Attending Surgeon
Lutheran Medical Center
Brooklyn, New York
|
| CAREER INTERESTS: |
CLINICAL: Reconstructive Surgery of the Hip and Knee, Orthopaedic Surgery in Metabolic Bone Disease
RESEARCH: The Biology of Skeletal Repair and Regeneration
|
| PROFESSIONAL ORGANIZATIONS: |
American Academy of Orthopaedic Surgeons
Orthopaedic Research Society
Orthopaedic Trauma Association
American Medical Association
American Society for Bone and Mineral Research
International Society for Fracture Repair
International Bone and Mineral Society
American Orthopaedic Association
American Institute for Medical and Biological Engineering
|
| NON-PROFESSIONAL ORGANIZATIONS: |
Achilles Track Club
Board of Directors,
1989 - Present
Confrerie des Chevaliers du Tastevin
1992 - 2005
|
| NATIONAL COMMITTEES AND OFFICES HELD: |
American Academy of Orthopaedic Surgeons:
Nominating Committee 2008 - 2009
Chairman, Council on Research and Scientific Affairs, 2000 - 2002
Chairman, Aging Committee, 1999 - 2000
Chairman, Task Force on Basic Science Education, 1994 - 1996
Chairman, Orthopaedic In-Training Examination, 1993 - 1996
Chairman, Committee on Evaluation, 1993 - 1996
Committee on Evaluation, 1990 - 1996
Council on Education, 1993 - 1996
Committee on Musculoskeletal Tumors and Diseases, 1991 - 1993
Orthopaedic Research Society:
Board of Directors, 1988 - 1998
President, 1995 - 1996
Secretary, 1991 - 1994
Chairman, Membership Committee, 1988 - 1989
Membership Committee, 1986 - 1989
American Board of Orthopaedic Surgery:
Question Writing Task Force
Written Certifying Examination, 1996 - 2006
Oral Examiner, 1998 - 2003
Orthopaedic Research and Education Foundation:
Board of Trustees, 2002 - Present
Vice Chair, Grants 2003 - 2009
National Osteoporosis Foundation:
Board of Trustees, 2001 - Present
Executive Committee, 2002 - 2007
Secretary, 2002 - 2007
Scientific Advisory Board, 1994 - 2001
The Paget Foundation:
Advisory Medical Panel, 1991 - Present
International Society for Fracture Repair:
Board of Directors, 1990 - 2002
President, 1998 - 2000
First Vice President, 1996 - 1998
Chairman, Publications Committee, 1990 - 1992
Second Vice President, 1992 - 1994
Orthopaedic Trauma Association:
Research Committee, 1993 - 1995
Nominating Committee, 2003 - 2004
American Orthopaedic Association:
Program Committee, 1993 - 1996
Chairman, 1995-1996
ABC Exchange Fellowship Committee,1994 - 2001
International Traveling Fellowship Committee, 1997 - 2000
Tissue Engineering Society:
Board of Governors, 1995 - 1997
Orthopaedic Political Action Committee:
Board of Directors, 1996 - 1998
|
| INSTITUTIONAL COMMITTEES AND OFFICES HELD: |
Boston University School of Medicine:
Dean's Executive Committee, 1997 - Present
Chairman, Search Committee for the Chairman of the Department of Rehabilitation Medicine, 1998 -1999
Chairman, Search Committee for the Chairman of the Department of Emergency Medicine, 2000 - 2001
Boston Medical Center:
Boston Medical Center Insurance Co., Inc.
Board of Directors, 2002 - 2008
Medical Executive Committee 1998 - Present
Operating Room Committee 1997 - Present
Operating Room Management Committee 1997 - 2000
Management Services Organization
Board of Directors 1998 - 2000
Chairman, Patient Satisfaction Committee 2006 - Present
Mount Sinai School of Medicine:
Executive Faculty, 1995 - 1997
Chairman, Instititutional Animal Care and Use Committee, 1990 - 1994
Research and Education Policy Committee, 1990 - 1994
Faculty Council, 1989 - 1992
|
| CORPORATE ADVISORY BOARDS: |
Global Steering Committee
Co-Chair
Stryker Biotech
Hopkinton, MA
2006 - Present
Scientific Advisory Board
Osteogenix
Palo Alto, CA
2006 - Present
Scientific Advisory Board
Osteotech, Inc.
Eatontown, NJ
2006 - Present
Scientific Advisory Board
Biosurface Engineering Technologies, Inc.
Rockville, MD
2006 - Present
Scientific Advisory Board
Anika Therapeutics
Woburn, Massachusetts
1999 - Present
Scientific Advisory Board
Skeletal Kinetics, LLC
Cupertino, CA
2003 - 2006
Osteoporosis Advisory Board
Eli Lilly, Inc.
Indianapolis, IN
2003 - 2006
Clinical Advisory Board
Auxeris Therapeutics, Inc.
St. Louis, MO
2004 - 2005
Orthopaedic Advisory Board
Merck & Co.
Whitehorse Station, NJ
2003 - 2005
Etoricoxib Advisory Board
Merck & Co.
Whitehorse Station, NJ
2001 - 2005
Scientific Advisory Board
Selective Genetics, Inc.
San Diego, California
1998 - 2002
Scientific Advisory Board
Orquest, Inc.
Mountain View, California
1994 - 1998
Scientific Advisory Board
Norian Corp.
Cupertino, California
1993-1999
|
| EDITORIAL BOARDS: |
Deputy Editor, Journal of Bone and Joint Surgery
1994 - Present
Associate Editor Journal of Orthopaedic Research
2005 - Present
Associate Editor, Bone
2004 - Present
Editorial Board,
1993-2003
Editorial Board, Journal of Bone and Mineral Research
1990 - Present
Editorial Review Board, Journal of the American Academy of Orthopaedic Surgeons
1993 - 1994
|
| AD HOC REVIEWER: |
Calcified Tissue International
Clinical Orthopaedics and Related Research
Endocrinology
Journal of the American Medical Association
Journal of Clinical Investigation
Journal of Orthopaedic Trauma
New England Journal of Medicine
Osteoporosis International
Science
Spine
|
| GRANT REVIEW COMMITTEES: |
National Institutes of Health
Skeletal Biology Development and Disease
Member Conflict Panel Chairman, November 16, 2005
National Institutes of Health
Special Emphasis Panel - Program Project Review Chairman, July 7, 2004
National Institutes of Health
Orthopaedics and Musculoskeletal Study Section
Member, October 13, 1993 - June 30, 1997
Chairman, October 18, 1995 - June 30, 1997
National Institutes of Health
Clinical Sciences Special Emphasis Panel
Chairman, August 13, 1998
National Institutes of Health
National Institute of Musculoskeletal and Skin Diseases
Multipurpose Arthritis Center - Review Committee
July 19 - 21, 1992
National Institutes of Health
Ad Hoc Special Review Committee
RFA Basic Research on Osteoporosis
1991
National Institutes of Health Special Study Sections:
Orthopaedics/Musculoskeletal
August 7, 1992
General Medicine A-2
October 7, 1991
Orthopaedic Research and Education Foundation
Research Grants Peer Review Committee
1991 - 1994
|
| SPECIAL CONSULTANT: |
Food and Drug Administration
Endocrinologic and Metabolic Drugs Advisory Committee
"Post-Menopausal Osteoporosis Treatment Drugs"
Bethesda, Maryland
November 17-18, 1994
Food and Drug Administration
Endocrinologic and Metabolic Drugs Advisory Committee
"Post-Menopausal Osteoporosis Treatment Drugs"
Bethesda, Maryland
May 7-8, 1992
|
| PEER REVIEWED GRANTS AWARDED (As PRINCIPAL INVESTIGATOR): |
National Institutes of Health - R01 AR055130
Hip Fracture Evaluation Alternatives of Total Hip vs Hemi-arthroplasty (HEALTH)
2008 - 2010, $574,270
National Institutes of Health - P01 AR049920
"Molecular Mechanisms of Skeletal Repair"
2004 - 2008, $3,500,000
Program Director: Thomas A. Einhorn, MD
Projects:
- "Role of Angiogenesis in Distraction Osteogenesis"
(PI: Louis C. Gerstenfeld, PhD))
- "Regulated Tissue-Specific BMP Function in Bone Repair"
(PI: Thomas A. Einhorn, MD)
- "Role of VEGF in Fracture Repair"
(PI: Dana Graves, DMD, DMSc)
Includes 3 Cores: Histomorphometry/Structural Analysis, Cellular and Molecular Biology, Administration
National Institutes of Health - R01 AR40701
"Cytokines in Fracture Healing"
1990 - 1995, $771,000
National Institutes of Health - R55 AR40701
"Gene Expression in Fracture Healing"
1991 - 1992, $100,000
Orthopaedic Trauma Association
"The Osteogenic Response to Bleeding and Intramedullary Trauma"
1994 - 1995, $19,604
Orthopaedic Research and Education Foundation
"Protein Degrading Enzymes at Physiological pH in Bone and Cartilage Calcification"
1986 - 1989, $132,706
Research Foundation S.U.N.Y.
Grant #E109L
"The Influence of Nutrition on the Mechanical Properties of Experimental Fracture Repair"
1982 - 1983, $3,000
|
| PEER REVIEWED GRANTS AWARDED (As CO-INVESTIGATOR): |
National Institutes of Health - R01-AR53353
"Inducing Skeletal Repair by Mechanical Stimulation"
Principal Investigator - Elise Morgan
2005-2009, $825,000
National Institutes of Health - R01-AR50243
"Healing of Segmental Defects in Bone by Gene Transfer"
Principal Investigator - Christopher Evans
2003-2008, $210,840
National Institutes of Health - R03 DE14963
"Role of Angiogenesis in Distraction Osteogenesis"
Principal Investigator - Roberto S. Carvalho
2003-2005, $100,00
US Army Medical Research and Material Command
"Assessment of Genetic Variation in Bone Fracture Healing"
Principal Investigator - Louis C. Gerstenfeld
2003-2005, $110,000
National Institutes of Health - R01-AR47045
"Functional Role of TNF-? Cytokines in Bone Repair"
Principal Investigator - Louis C. Gerstenfeld
2001-2005, $850,000
Arthritis Foundation
"The Generation of Articular Cartilage and Joint Structure in a Bone Gap Using Controlled Micromotion"
Principal Investigator - Dennis M. Cullinane
2001 - 2004, $222,000
National Institutes of Health - R43-AR43107
"Mechanical Stimulation of Fracture Healing by Ultrasound"
Principal Investigator - James T. Ryaby
1995 - 1996, $99,535
National Institutes of Health - R43-AR43045
"Ultrasonic Assessment of Bone Using Neural Networks"
Principal Investigator - Jonathan J. Kaufman
1994 - 1995, $75,000
Orthopaedic Research and Education Foundation - #90-523
"Osteoblast Attachment to Extracellular Matrix Molecules"
Principal Investigator - Robert J. Majeska
1989-1991, $79,738
|
| CORPORATE GRANTS AWARDED (AS PRINCIPAL INVESTIGATOR): |
Amgen, Inc.
"Comparison of Two Anti-Resorptive Therapies (Alendronate versus AMG 162 Monoclonal Anti-RANKL)"
2006 $36,772
GlaxoSmithKline
"Comparison of SB768974 and SB751689 to Low-Dose Parathyroid Hormone in the Enhancement of Experimental Fracture Healing"
2006 - 2007 $162,000
Stryker Biotech
"Synergism between OP-1 and PTH in a Rabbit Model of Tibial Healing"
2005 -2006 $170,104
Biosurface Engineering Technologies, Inc.
"Therapeutic Potential of B2A2 in Enhancement of Normal Fracture Repair Principal"
2005 $26,000
Eli Lilly, Inc.
"Effect of Teriparatide on Distal Radius Fracture Healing"
2004-2006, $67,000
BioMimetic Pharmaceuticals, Inc.
"Enhancement of Experimental Fracture Healing with PDGF"
2004-2005, $55,011
Eli Lilly, Inc.
"Role of PTH(1-34) in the Enhancement of Fracture Healing"
2002-2003, $144,291
Monsanto/Searle Corp.
"Role of COX-2 Specific Inhibitors in Skeletal Repair"
2001 - 2003, $289,140
DePuy, Inc.
"Assessment of Multiple Pharmacological Therapies for the Enhancement of Fracture Healing"
2000-2001, $222,011
Stryker Biotech
"Fracture Repair with OP-1 in Conjunction with Conventional NSAIDs" 2001-2002, $95,659
Bayer Corp.
"Effects of Specific Growth Factors and Pharmacological Compounds on Fracture Healing"
2000-2001, $109,629
EBI Corp.
"Effects of FGF-9 on Fracture Healing"
2000-2001, $46,421
Monsanto/Searle Corp.
"Effects of COX-2 Specific and Non-specific NSAIDs on Fracture Healing"
1999-2000, $86,328
Procter and Gamble
"Enhancement of Experimental Fracture Healing with Prostamimetic Agents"
1998-1999, $60,000
Genetics Institute
"Enhancement of Fracture Healing with an Injectable Preparation of BMP-2"
1995-1997, $118,000
Procter and Gamble
"Enhancement of Experimental Fracture Healing with PTH"
1995-1997, $75,000
Howmedica Corp.
"Attachment of Osteoblastic and Non-osteoblastic Cells to Orthopaedic Implants using Extracellular Matrix Proteins"
1992-1993, $75,000
|
| VISITING PROFESSORSHIPS AND NAMED LECTURESHIPS: |
Talking Proud Lecturer
University of Buffalo
Department of Orthopaedic Surgery
Buffalo, New York
October 17 -18, 1984
Visiting Professor of Orthopaedic Surgery
Hebrew University-Hadassah Medical Center
Jerusalem, Israel
March 12 - 16, 1986
Visiting Distinguished Scientist
Hospital Eugenio Espejo
Quito, Ecuador
February 19 - 21, 1988
Distinguished Lecturer
Department of Orthopaedics and Rehabilitation
University of New Mexico
Alburquerque, New Mexico
June 7 - 8, 1991
Samuel Higby Camp Lectureship
University of Michigan Medical School
Ann Arbor, Michigan
April 21 - 22, 1993
Visiting Professor of Orthopaedic Surgery
Department of Orthopaedics
University of Medicine and Dentistry of New Jersey
New Jersey Medical School
Newark, New Jersey
June 2 - 3, 1993
Visiting Professor of Orthopaedic Surgery
Bone and Joint Center
Henry Ford Hospital
Detroit, Michigan
May 8 - 9, 1994
Visiting Professor of Orthopaedic Surgery
Department of Orthopaedic Surgery
University of Pittsburgh
Pittsburgh, Pennsylvania
April 25 - 26, 1995
Visiting Professor of Orthopaedics
Department of Orthopaedics
Milton S. Hershey Medical Center
Hershey, Pennsylvania
May 2 - 3, 1995
Visiting Professor of Orthopaedics and Keynote Speaker
Fourth Annual Research Day
Orthopaedic Hospital
Los Angeles, California
May 22 - 23, 1995
Visiting Professor of Orthopaedics
Case Western Reserve University
Cleveland, Ohio
September 29 - 30, 1995
Patrick J. Kelly Visiting Professor
Department of Orthopaedics
Mayo Clinic
Rochester, Minnesota
November 17 - 19, 1995
Annual Basic Science Visiting Professor
Grand Rapids Orthopaedic Surgery Residency Program
Grand Rapids, Michigan
October 29 - 30, 1996
Visiting Professor
Division of Endocrinology
Mayo Clinic
Rochester, Minnesota
August 18 - 19, 1997
Mallory-Coleman Visiting Professor
Division of Orthopaedic Surgery
Ohio State University
Columbus, Ohio
June 10 - 11, 1998
Robert W. Johnson, Jr. Visiting Professor
The Johns Hopkins Medical Institutions
Department of Orthopaedic Surgery
Baltimore, Maryland
June 18 - 19, 1998
Harry J. Reicher Memorial Lectureship
New York University - Hospital for Joint Diseases
Department of Orthopaedic Surgery
New York, New York
December 17, 1998
Lauren Ackerman, M.D., Memorial Lecturer
The State University of New York at Stony Brook
Department of Orthopaedics and Program in Biomedical Engineering
Stony Brook, New York
May 12, 1999
Marshall J. Schiff, M. D. Memorial Lectureship
American College of Rheumatology
Philadelphia, Pennsylvania
October 30, 2000
SORT-IT Lecturer
Scottish Orthopaedic Research Trust into Trauma
Edinburgh, Scotland
August 16, 2001
Distinguished Lecturer
Department of Orthopaedic Surgery
Washington University School of Medicine
St. Louis, Missouri
March 27-28, 2002
R. Plato Schwartz Visiting Professor
Department of Orthopaedic Surgery
University of Rochester Medical Center
Rochester, New York
May 10-11, 2002
James B. Wray, MD Visitng Professor
Department of Orthopaedic Surgery
Indiana University
Indianapolis, Indiana
June 5-7, 2002
Visiting Professor Pro Tempore
Department of Orthopaedic Surgery
The Cleveland Clinic Foundation
Cleveland, Ohio
June 12-14, 2002
Visiting Professor
Department of Orthopaedic Surgery
Carolinas Medical Center
Charlotte, North Carolina
June 18-20, 2002
J.F.L. Woodbury Lecturer in Rheumatology
Department of Medicine
Dalhousie University
Halifax, Nova Scotia
May 6, 2003
Visiting Professor and Jeannette Wilkins Memorial Lecturer
University of Southern California - Graduate Orthopaedic Society
Los Angeles, California
June 19-20, 2003
Endocrine Scholar Lecturer
Division of Endocrinology and Metabolsim
University of Connecticut Health Center
Farmington, Connecticut
February 10, 2004
Visiting Professor of Orthopaedic Surgery
Fourth Annual Resident Research Day
St. Luke's-Roosevelt Hospital Center
New York, New York
June 17, 2004
Distinguished Lecturer
The Hospital for Special Surgery
New York, New York
September 10, 2004
Wesley Burnham Lecturer
Hennepin County Medical Center
34th Annual Orthopaedic and Trauma Seminar
November 11-13, 2004
Leo Leung Memorial Lecturer
Department of Orthopaedic Surgery
University of Pennsylvania
Philadelphia, Pennsylvania
May 5, 2005
Visiting Professor
Trauma and Orthopaedic Department
University of Leeds
Leeds, United Kingdom
February 8-10, 2006
Keynote Lecturer
2nd World Veterinary Orthopaedic Congress and 33rd Annual Veterinary Orthopaedic Society Meeting
Keystone, Colorado
February 26, 2006
Visiting Professor
Department of Orthopaedic Surgery
Stanford University - Research Day
Palo Alto, California
March 11, 2006
Rex L. Diveley Visiting Professor
Department of Orthopaedic Surgery
University of Missouri - Kansas City
Kansas City, Missouri
May 4-6, 2006
Visiting Professor
Department of Orthopaedic Surgery
University of Iowa
Senior Residents Day
Iowa City, Iowa
June 2-3, 2006
Visiting Professor
Department of Orthopaedic Surgery
University of California, Davis Health System
Paul R. Lipscomb Alumni Society
Sacramento, California
June 21-22, 2007
John W. Frymoyer Lecturer
Department of Orthopaedics and Rehabilitation
University of Vermont College of Medicine
Burlington, Vermont
September 19 - 20, 2007
Chief Scientist Pro-Tempore
Torsten N. Wiesel Lecturer
Hospital for Special Surgery
New York, New York
November 13 - 15, 2008
Visiting Distinguished Professor
Department of Orthopaedic Surgery
Case Western Reserve University
University Hospitals Case Medical Center
March 31 - April 1, 2009
|
| MEDICAL INVENTIONS: |
"Einhorn Bone Biopsy System"
U.S. Patent No. 4,782,833
Stryker Corporation (licensee)
Kalamazoo, Michigan |
